Senior Research Associate, Protein Sciences

Austin, TX, USA
Feb 15, 2021
Science/R&D, Research
Lone Star Bio
Required Education
Associate Degree
Position Type
Full time
Company Overview:

Molecular Templates (MTEM) is a clinical stage biopharmaceutical company developing targeted therapeutics using its innovative proprietary Engineered Toxin Body (ETB) platform. MTEM's first immunotoxin, MT-3724, is in clinical development for non-Hodgkin's lymphoma. Pipeline products for additional targets and indications are being advanced toward clinical development. For more information, please visit MTEM's website at:

Position Overview:

The Senior Research Associate (Sr. RA) is an integral member of the research and development (R&D) team and will be involved in ETB protein production and analysis. This is a laboratory-based position in a team setting. The Sr. RA will be responsible for conducting protein production and analysis tasks based on established protocol, or will participate in the development of new protocols, with all work being documented. The Sr. RA may be assigned to work with less experienced RA team members to train and mentor them. The Sr. RA may be asked to work on projects with less direct supervision and/or that are more critical to overall research goals and will be expected to apply good judgment within defined procedures and practices to determine appropriate actions. Responsibilities may change in line with prioritization at the discretion of the management team.

Job Responsibilities will include:
  • Performs research and/or development in collaboration with others for projects.
  • Analyze data, evaluate results, form conclusions, and provide input to support next steps.
  • Under the supervision and direction of management, assists in investigating, creating and developing new methods and technologies for project advancement.
  • Maintains a high level of professional expertise through familiarity with internal training and scientific literature, as appropriate for the level of work assigned.
  • Presents data and methods in R&D meetings, as needed and assigned.
  • Produces and purifies ETB proteins in an E. coli- based expression system according to established protocols.
  • Conducts analytical protein assays according to established protocols.
  • Accurately documents all tasks in a timely manner.
  • Actively engages in the design and execution of new experiments, test protocols and improvement of current work processes, as needed under the direction of management.
  • Supports management with the onboarding, training and mentoring of more junior lab personnel.
  • Expected to work with minimal supervision, receiving little instruction on routine work and general instruction on new projects or assignments.
  • Other tasks may be assigned, including independent projects, as needed.

  • A Bachelor's degree in a life science, chemistry, pharmaceutical science or related field is strongly preferred.
  • 3-5 years of lab-based experience (academic or industry) is required.
  • Ability to work on problems of moderate scope where analysis of situations or data requires a review of a variety of factors.
  • Demonstrated ability to safely follow detailed directions and protocols in a laboratory environment and to use experience and expertise to suggest improvements to management.
  • Relevant experience in a laboratory setting involving molecular biology and recombinant protein expression from a prokaryotic (E. coli) system is required.
  • Proficiency in operating bioreactor or FPLC systems is required.
  • Experience conducting analytical protein assays (i.e. A280, SDS-PAGE and HPLC).
  • Ability to work in a fast-paced, team environment.
  • Ability to build stable working relationships with team members.
  • Strong time-management skills.
  • Strong written and verbal communication skills.
  • Computer skills with knowledge of spreadsheet and word processing software.

Reporting Structure:

This position reports to R&D management. This can vary in level depending on the specific assignments.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc