Scientist, Translational Science

Location
Cambridge, MA, United States
Posted
Feb 11, 2021
Ref
R20
Hotbed
Genetown
Required Education
Bachelors Degree
Position Type
Full time
Our Mission: Developing curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

At Intellia, we are committed to solving the complex challenges of making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to create novel engineered cell therapies for immuno-oncological and autoimmune diseases.

Job Description:

SUMMARY:

Intellia is seeking a highly skilled and motivated Scientist to join the Translational Science Team. The primary responsibility for this position will be to develop, optimize, and validate bioanalytical assays to support late stage preclinical and clinical studies. Work will be done independently and in collaboration with colleagues to achieve efficient delivery of CRISPR/Cas9 therapeutics. Applicants should have exceptional research, organizational, and communication skills (both written and oral) coupled with a strong attention to details.

RESPONSIBILITIES:
  • Develop, optimize, and troubleshoot ligand binding, enzymatic activity, and cell-based assays to support pipeline programs
  • Generate critical assay reagents (e.g. biotinylate, sulfo-tag)
  • Assist in transfer of analytical methods to external labs
  • Perform routine and non-routine analytical testing of study samples
  • Conduct experiments, independently and in collaboration with colleagues, in support of project goals
  • Communicate findings with internal and external teams/partners in a clear and concise manner
  • Assist in maintaining general laboratory functionality, including lab equipment maintenance and ordering and receipt of lab supplies
  • Diligent and timely documentation of experiments in ELN and reports


QUALIFICATIONS:
  • BS in biology or similar area with 9+ years industrial experience, MS in biology with 6+ years relevant experience
  • Experience with proteins/antibodies and development and optimization of ligand binding assays across multiple platforms (ELISA, Luminex, and/or MSD)
  • Experience with cell culture and maintenance
  • GLP/GCLP familiarity/experience is desired
  • Knowledge of regulatory expectations with respect to bioanalysis/immunogenicity preferred
  • Experience with technology transfers of assays to CRO's is highly valuable
  • Must be a team player with good interpersonal and organizational skills


EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.