Senior Formulation Scientist

Overview

We are currently searching for a Senior Formulation Scientist to provide support to the National Institutes of Health (NIH). This opportunity is a full-time position with MSC and it is on-site in Gaithersburg, Maryland.

Duties & Responsibilities

• Lead a project team for the evaluation and development of stable formulations in the liquid or frozen state (project dependent) for the vaccine candidates at the center, including the following subtasks:
  • Work with the Director of Formulation, Project Management, and Functional Leads from other process teams to develop a formulation development plan, including timeline, that is dictated by the specific product TPP and project requirements.
  • Design fit-for-purpose formulation and stability studies.
  • Oversee the technical execution of those studies by Formulation personnel, and personally execute studies as needed.
  • Analyze, collate and interpret study data (directly and that analyzed by team members) based on technical expertise, previous project experience, organization knowledge and accepted scientific field literature.
  • Develop and execute assays for biological product characterization, formulation development and stability testing of recombinant protein-based vaccines, proteinaceous nanoparticles, and virus-like particles.
  • Analyze, interpret and present data in small group, department and conference settings.
  • Write and review technical reports and protocols documenting formulation, stability and method development studies.
  • Contribute directly to regulatory filings in collaboration
• Represent the department and/or the center/program in one or more of the following
  • Cross functional teams with center/program development personnel to facilitate overall project objectives.
  • Cross functional teams with GMP personnel to facilitate transfer of development procedures to GMP facilities.
  • Cross functional teams with external stakeholders as required by project.
  • Provide strategic guidance and technical instruction to formulation team members.
  • Work in collaboration with personnel to generate and complete professional development goals.

Requirements

• Ph.D. in Pharmaceutics, Chemistry, Biochemistry, or a related discipline. An M.S. plus three (3) years of relevant experience may be considered equivalent to a Ph.D.
• Minimum of eight (8) years of related laboratory experience required.
• Three to eight (3-8) years of industry or industry equivalent non-profit experience in protein and/or protein based vaccine formulation development.
• Experience in leading a formulation development project, including,
  • Calorimetric analysis (Differential Scanning Calorimetry and Isothermal Chemical Denaturation)
  • Circular Dichroism, Intrinsic and extrinsic Fluorescence and Uv-Visible spectroscopies
  • Particle analysis (MFI, Nanosight, DLS, LO/HIAC)
  • Classic protein biochemistry sample handling and analysis (UF/DF, SDS-PAGE, Western Blot)
  • Chromatography (SEC, RP)
• Experience in active participation on cross-functional project teams.
• Experience in data analysis and experimental design software packages (e.g. Prism, SigmaPlot, MicroCal Origin, JMP, etc.)

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Company Description

We are a trusted government partner that blends deep domain expertise with advanced technologies to help our customers solve complex problems that improve, protect, and save lives. As a rapidly growing company, we combine entrepreneurial spirit, customer focus, and an outcomes-based approach to support agency missions in health IT, life sciences, public safety, and grants management.

The Dovel Family of Companies offers employees an opportunity to advance beyond a specific role or contract, we offer a path to develop an enriching career. We believe in empowering a culture of innovation, customer success, and employee growth.

What you'll get...

• Time Off! Flexible schedules and company paid holidays allow you to take the time you need.
• Investment in YOU! 401(K) company contributions are yours to keep with no waiting period.
• Choices! Unique healthcare plans to choose from with options like fertility and orthodontia benefits.
• Discovery! With our tuition assistance and training programs, we support your career advancement.
• Tax Savings! Enroll in pre-tax Health or Dependent Care Flexible Spending, HSA with company contributions, parking, and/or transit commuter benefits.
• Support! Working parents and busy professionals - we've got you covered with a supportive culture, confidential Employee Assistance Program and a membership to Care.com.
• Perks! Employee discounts, peer recognition programs, company-wide wellness challenges, and fun community events.
• A Voice! A unique culture where you can influence decisions and have your voice heard.

We are an Equal Opportunity Employer with a commitment to diversity. All individuals, regardless of personal characteristics, are encouraged to apply. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, sexual orientation, gender identity, disability, or veteran status.