Research Associate iPS-T Cell Differentiation

Location
Cambridge
Posted
Feb 11, 2021
Ref
4637554002
Discipline
Science/R&D, Research
Required Education
Bachelors Degree
Position Type
Full time
JOB PURPOSE

We are seeking an energetic and detail-oriented laboratory scientist with experience in pluripotent stem cell culture to join a growing cell therapy team. Under the supervision of a principal scientist, the associate will be responsible for experiments designed to characterize and optimize the differentiation of iPSCs into lymphoid cells to support the iPS-T cell therapeutic program.

DUTIES AND RESPONSIBILITIES
  • Culture of primary, immortalized and/or pluripotent stem cells
  • Make observations, interpret results, and document experimental methods in a well-maintained laboratory notebook
  • Analysis of cell state and identity by assays including qPCR, FACS, and immunofluorescent microscopy
  • Genome engineering of cells using CRISPR/Cas9
  • Design and execution of assays to measure hematopoietic potential of cells
  • Independently design, perform, and interpret experiments
  • Work collaboratively with scientists in a cross-functional or matrixed team environment
  • Ability to collaboratively work with scientists in a cross-functional or matrixed team environment.
  • Present findings to peers and company in meetings

QUALIFICATIONS
  • Bachelors' degree in a life sciences discipline such as biology, molecular biology, biochemistry, or pharmacology with 2+ years of laboratory experience.
  • Demonstrated expertise in modern cell and molecular laboratory techniques and functions is required
  • Proficiency in common office software (typically Microsoft Word, Excel and PowerPoint).
  • Prior experience culturing and differentiating human pluripotent (ES/IPS) stem cells is strongly preferred
  • Expertise in multi-color flow cytometry is strongly preferred