Research Associate, Discovery Operations

Brisbane, CA, United States
Feb 10, 2021
Biotech Bay
Required Education
Associate Degree
Position Type
Full time

Mammoth Biosciences is harnessing the diversity of nature to power the next-generation of CRISPR products. Through the discovery and development of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. By leveraging its internal research and development and exclusive licensing to patents related to Cas12, Cas13, Cas14 and CasPhi, Mammoth Biosciences can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Mammoth is democratizing disease detection with easy and affordable point-of-care tests that allow real-time and simultaneous detection of multiple conditions, along with high-throughput tests that allow for unprecedented testing volume. Further, the company is transforming disease treatment with its proprietary micro-sized CRISPR proteins that enable new editing and delivery options. Based in Brisbane, CA, Mammoth Biosciences is co-founded by CRISPR pioneer Jennifer Doudna and principal founders Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Decheng, Mayfield, NFX, and 8VC, and leading individual investors including Brook Byers, Tim Cook, Bob Nelsen, and Jeff Huber.


Mammoth is seeking a Research Associate with molecular biology and biochemistry expertise to join its growing Discovery team. The Discovery team is responsible for developing novel CRISPR-associated (Cas) nucleases for genome editing and diagnostic applications.

The successful candidate will be responsible for executing laboratory workflows to develop Cas nucleases genome editing and diagnostic applications. They will have the opportunity to contribute broadly across multiple technical areas, including plasmid construction, NGS assays, protein purification and high-throughput screening. This is an excellent development opportunity for researchers who want to learn new skills and start their career working on cutting-edge CRISPR technologies.

    • Execution of established molecular biology and biochemistry workflows (functional assays and reagent preparation)
    • Document and regularly present data at internal meetings
    • Other duties as assigned

    • BS or MS or in molecular biology, biochemistry, or a related field
    • 1 year of relevant laboratory research experience

    • Hands-on experience in one or more of the following areas: plasmid assembly, protein purification (E. coli-based expression, FPLC & SDS PAGE), enzyme kinetics. Next Generation Sequencing (NGS) assays, automated liquid handlers and/or colony pickers
    • Computer and scripting skills (Benchling, Geneious, JMP, SQL, R, python)

    • Company-paid health/vision/dental benefits
    • Unlimited vacation and generous sick time
    • Company-sponsored meals and snacks
    • Wellness, caregiver and ergonomics benefits
    • 401(k) with company matching