Contract Associate Scientist \u2013 Translational Immunology

Location
Cambridge, MA, United States
Posted
Feb 10, 2021
Ref
345290020
Hotbed
Genetown
Required Education
Bachelors Degree
Position Type
Full time
The Company

Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, is engineering a novel class of injectable biologics to selectively engage and modulate targeted T cells within the body to transform the treatment of cancer and autoimmune diseases. Cue Biopharma is a high growth company and is listed on NASDAQ (CUE). The company is located in Cambridge, Massachusetts in the heart of the life sciences corridor.

Cue Biopharma is building a world-class team of highly motivated, dedicated scientists to help us advance our research and development programs. The company culture is fast-paced and committed to scientific excellence, innovation, and teamwork.

Candidate Profile

We are looking for a motivated Contract Associate Scientist to join our Translational Immunology/Immuno-Oncology group to provide key mechanistic, pre-clinical and translational support for Cue Biopharma's growing pipeline. The Contract Associate Scientist will be part of the company's TCR Core, a team dedicated to generating and performing key studies with T Cell Receptors - TCR-transduced human cell lines and primary human T cells. This is a temporary contract position that could last up to six (6) months.

Key Responsibilities
  • Planning, executing and analyzing in vitro/ex vivo studies using primary human immune cells (from healthy donors and patients).
  • Isolation, lentiviral transduction and culture of primary human and non-human PBMCs and immune cell subsets.
  • Expansion, selection and long-term maintenance of T cell clones/lines.
  • Immunophenotyping using multicolor flow cytometry staining.
  • Conduct experiments, accurately document and effectively communicate data with project team, colleagues and manager.
  • Contribute collaboratively to team efforts to achieve experimental and organizational goals.

Requirements
  • B.S. in a relevant field with 2-4 years of related laboratory experience. Or M.S. in a relevant field with 0-2 years of related laboratory experience. Hands-on industry experience executing and documenting in vitro biology studies is preferred. Preference for experience with working with primary human immune cells.
  • Experience with multiple transfection/transduction methodologies to generate transient and stably transfected cell lines and primary cells; multicolor flow cytometry, FACS-based immunophenotyping; cellular immunology in vitro assays is highly desirable.
  • Scientifically rigorous, highly organized, and displays significant attention to detail.
  • Self-motivated and able to work independently.
  • Team and goal-oriented scientist with excellent oral and written communication skills who enjoys working in a fast-paced, small-company environment.