Associate Scientist, Quality Control

Location
San Diego, CA, United States
Posted
Feb 06, 2021
Ref
457SW
Required Education
Masters Degree/MBA
Position Type
Full time
Fate Therapeutics is seeking a highly motivated Quality Control (QC) Associate Scientist with flow cytometry, qPCR, and/or cell-based assays experience to support its expanding cellular therapy programs. This role will execute tests for manufacturing in-process control (IPC), lot release, and stability testing of clinical drug product within a GXP environment. Additionally, this role may participate in troubleshooting QC testing and method qualification. The successful candidate will be adept at executing analytical test methods, working with mammalian cell culture, and analyzing emerging data to assess the characteristics of hematopoietic and stem cell-based therapeutics. This is a full-time position reporting to a Scientist, Quality Control and is located at our corporate headquarters in San Diego, CA.

Responsibilities
• Perform in-process control, lot release, and stability testing using flow cytometry, qPCR, and/or
cell-based assays
• Ensure proper and timely completion of testing and tasks as assigned
• Report results in detailed and organized presentations and reports
• Participate in cross-functional training and identifying and facilitating continuous improvements
• Participate in technical transfer, qualification and validation protocols for QC assays
• Maintain instrumentation and equipment preventative maintenance and supporting documentation in a cGMP compliant manner
• Onboard new materials and reagents
• Identify and support initiation and completion of deviations, CAPAs, and laboratory investigations

Qualifications
• M.S. or B.S. degree in a scientific discipline with minimum of 5 years of biotechnology, clinical,
or pharmaceutical laboratory experience is required.
• Prior experience working in a regulated environment (e.g., GMP, GLP, or CLIA) is highly preferred.
• Hands on experimental skills with flow cytometry, qPCR, ddPCR, ELISA or cell-based assays is necessary. Multi-color flow cytometry is preferred.
• Proficiency with aseptic techniques for working with cell culture, human blood, and blood products is desired.
• Strong scientific, analytical, problem solving, and communication skills as well as sound judgment, with the ability to work both independently and effectively with others.
• Highly organized, detail oriented with excellent record keeping abilities, and computer
proficiency.
• Ability to work independently in a high paced team environment, to prioritize activities from multiple projects with little supervision.

Working Conditions and Physical Requirements
• Will require working with cells and cell lines of human and/or animal origin
• Occasional evening and weekend work will be required
• 100% on-site work at corporate headquarters in San Diego, CA
The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. For consideration send cover letter and curriculum vitae to: careers@fatetherapeutics.com and reference job 457SW.

About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-in-class cellular immunotherapies for cancer and immune disorders. The Company has established a leadership position in the clinical development and manufacture of universal, off-the-shelf cell products using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company's immuno-oncology product candidates include natural killer (NK) cell and T-cell cancer immunotherapies, which are designed to synergize with well-established cancer therapies, including immune checkpoint inhibitors and monoclonal antibodies, and to target tumor-associated antigens with chimeric antigen receptors (CARs). The Company's immuno-regulatory product candidates include ProTmune™, a pharmacologically modulated, donor cell graft that is currently being evaluated in a Phase 2 clinical trial for the prevention of graft-versus-host disease, and a myeloid-derived suppressor cell immunotherapy for promoting immune tolerance in patients with immune disorders. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.