Senior Scientist / Scientist, Cancer Immunotherapy (Solid Tumor)
- Employer
- Fate Therapeutics
- Location
- San Diego, CA, United States
- Start date
- Feb 4, 2021
View more
- Discipline
- Science/R&D, Biotechnology, Immunology, Oncology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
Job Details
Responsibilities
include
• Leverage NK cell biology, tumor immunology, or cancer biology expertise in collaborative efforts with Scientists, Associate Scientists and Research Associates to develop, influence and enhance our understanding of NK cell products.
• Design, plan, execute and manage proof of concept studies spanning multiple programs to assess NK cell products' fitness and function.
• Phenotypic and functional analysis of NK cells using multi-color flow cytometry, gene expression, and cytokine production.
• Viral vector-based modification of cell lines and primary cells.
• Aseptic culture techniques of tumor, NK cells, and cell lines.
• Perform in vitro cytotoxicity assays and in vivo xenograft tumor models to evaluate immune-oncology product candidates.
• Collect, maintain, and organize primary data and analysis accurately and timely in accordance with company policy.
• Prepare and present data to team members and larger multidisciplinary teams.
• Take initiative to perform routine laboratory tasks and upkeep of the lab space in order to maintain conditions that are conducive to excellent scientific work.
Requirements
• Ph.D. in Immunology, cancer cell biology (or a related field) with 2+ years of relevant laboratory experience in an academic, biotechnology, or pharmaceutical setting.
• Experience with mammalian cell culture, ideally with in vitro assessment of lymphocyte effector functions including tumor cell cytotoxicity killing assay and cytokine production is highly desirable.
• Experience with multi-laser flow cytometry instruments, high dimension analysis software and the ability to design extensive flow cytometry panels is highly desirable.
• Excellent coordination and communication with multiple groups for scheduling and execution of experiments.
• Excellent data organization, analysis, and troubleshooting skills using Prism or Spotfire.
• Positive outlook, willingness to learn and contribute, and a team-oriented attitude.
• Excellent written and oral communication skills.
Working conditions and physical requirements
• Will require working with cells and cell lines of human and/or animal origin
• Occasional weekend and/or evening hours required
• 100% on site work at corporate headquarters in San Diego, CA The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time. For consideration send cover letter and resume to: careers@fatetherapeutics.com and reference job
code 412AG.
About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to the development of first-
in-class cellular immunotherapies for cancer and immune disorders. The Company has established a
leadership position in the clinical development and manufacture of universal, off-the-shelf cell products
using its proprietary induced pluripotent stem cell (iPSC) product platform. The Company's immuno-
oncology product candidates include natural killer (NK) cell and T-cell cancer immunotherapies, which
are designed to synergize with well-established cancer therapies, including immune checkpoint
inhibitors and monoclonal antibodies, and to target tumor-associated antigens with chimeric antigen
receptors (CARs). The Company's immuno-regulatory product candidates include ProTmune™, a
pharmacologically modulated, donor cell graft that is currently being evaluated in a Phase 2 clinical trial
for the prevention of graft-versus-host disease, and a myeloid-derived suppressor cell immunotherapy
for promoting immune tolerance in patients with immune disorders. Fate Therapeutics is headquartered
in San Diego, CA. For more information, please visit www.fatetherapeutics.com.
Company
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a first-in-class pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients with cancer and autoimmune disorders. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s effector cell pipeline includes multiplexed-engineered, iPSC-derived natural killer (NK) cell and T-cell product candidates, which incorporate novel synthetic controls of cell function, such as chimeric antigen receptors (CARs) to target tumor-associated antigens and are intended to deliver multiple mechanisms of therapeutic importance to patients including in combination with well-established cancer therapies. Fate Therapeutics is headquartered in San Diego, CA. For more information, please visit www.fatetherapeutics.com.
- Website
- http://www.fatetherapeutics.com/
- Phone
- 858.875.1800
- Location
-
12278 Scripps Summit Drive
San Diego
California
92131
United States
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