AbbVie

Sr. Scientist, Neurotoxin & Biologics Analytical Sciences

Employer
AbbVie
Location
Irvine, CA, United States
Posted
Feb 04, 2021
Ref
2101685
Required Education
Doctorate/PHD/MD
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

Envision working with energetic colleagues and inspirational leaders. Now, place yourself in that mix; leading discussions, asking the right questions and driving results.

What Your New Manager Wants You To Know

The Sr. Scientist is responsible for supporting the development qualification, transfer and validation of analytical methods for the characterization of proteins and peptides. This position will have an emphasis in Biophysical Characterization (UV, fluorescence, light scattering, subvisible particle analysis, CD, AUC, DSC, ITC). He/She will provide scientific leadership as an expert across the R&D functional groups and in different project teams for the analytical characterization of biological drugs (i.e. proteins, peptides, protein mixtures). He/She independently plans experimental work and executes protocols in support of biologics process development, formulation development, and stability studies. The individual independently generates, compiles, and evaluates data for technical reports to support regulatory filings for new and currently marketed biological products. The individual is also responsible for writing sections or subsections of Technical Reports and Method or Operational SOPs. He/She independently carries out multiple analytical methods to support AbbVie biologics projects depending on departmental needs. Maintains a productive and collaborative laboratory environment consistent with regulatory and company expectations.

YOU ARE more than just a title, YOU ARE...

A strategic thinker: align and excite internal stakeholders to facilitate success through strong leadership, strategic thinking and personal drive.

First class team player: collaborate across multiple disciplines to ensure compliance and ability to influence cross-functional teams and senior leadership.

You Will
  • Execute the development of analytical techniques for the characterization of biopharmaceuticals with an emphasis on biophysical characterization. Create written procedures and protocols. Transfer, qualify or validate analytical methods as needed. Mentor staff within a matrix environment when needed.
  • Apply routine and specialized analytical techniques to characterize and quantify biopharmaceuticals. Maintain reagent supplies, notebooks, summarizes results in written reports and communicates observations to ensure that the end user receives quality methods in a timely manner. Comply with Quality Principals related to data generation and reporting.
  • Actively participate on cross-functional teams within Biologics Development and provide support to external departments. Openly share scientific expertise and collaboratively help the team to formulate rational solutions to problems.
  • Develop protocols and SOPs, train staff and maintain the laboratory consistent with departmental and AbbVie requirements. Understand, document, and adjust Quality Systems to match the project stage (e.g. pre-development or development).
  • Maintain a good and current knowledge of the scientific and technical literature pertinent to the project and necessary for development of state-of-the-art analytical methods, including the acquisition of reasonable and necessary equipment.
  • Keep up-to-date on current and cutting-edge developments in the biologics characterization field.
  • Make high quality scientific presentations at internal management, regional and national meetings to help advance AbbVie's image as the thought and product leader in the neuromodulator field. Present and defends product, assay and process data to regulatory agencies.

Qualifications

You Bring
PhD in Biological Science, Biochemistry, Protein Chemistry, Biochemical/Chemical Engineering or a related Life Science field with 5-10 years of relevant industrial experience or MS with 12+ years related work experience.
  • Extensive experience with the application of biophysical techniques for the characterization of proteins and their degradation and modification products.
  • Skilled in the use of multiple types of equipment for the characterization of proteins or peptides
  • Working knowledge of the requirements of working in a GLP or cGMP environment is helpful.
  • A solid understanding of methods and procedures related to the production and characterization of biopharmaceuticals in a regulated environment is expected.
  • A strong analytical and instrument skills and a thorough understanding and working knowledge of analytical method development and validation.

In this role, we're looking for a leader who will:
  • Act as an Owner
  • Be Excellence Focused
  • Act as an Influencer

We Will Give You 'The AbbVie Edge'

At Abbvie, we define an 'edge' as something that sets us apart, gives us an advantage and strengthens us to be better - for our customers, patients, investors and each other. Our 'edge' is our colleagues, and we are committed to making Abbvie the best place for them to work and achieve career goals.

How do we do this? We Engage, Develop, and Reward our colleagues.

Engage. From Day 1, you are a bold leader who wants to make an impact. We listen to your ideas and questions, so we can be even better at what we do.

Develop. Learn every day, build new skills every day. We prioritize development, so our leaders are always ready for the next challenge and opportunity.

Reward. Exceptional performance creates exceptional opportunities and rewards. Financial awards and incentives are just a part of this - we invest in our people; celebrate success through recognition programs; and promote healthy lifestyles and work-life balance.

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
IC
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.