Medicinal Chemist

San Diego, CA
Feb 03, 2021
Required Education
Position Type
Full time


VersaPeutics, Inc is a growing startup company based in San Diego, California. We are developing novel therapeutics for a variety of disease indications with a focus on central nervous system diseases and oncology. We are seeking an experienced chemist to co-lead our small molecule drug discovery program with our experienced biologists.


  • Provide hands-on leadership in the design, synthesis and characterization of molecules as part of drug discovery efforts
  • Evaluate the data on potency, in vitro ADME and pharmacokinetic information in the development of Structure Activity Relationships (SAR) and its application to lead optimization
  • Collaborate as part of integrated, cross-functional program teams towards the advancement of high-quality drug candidates into clinical development
  • Proactively share drug discovery and development experience with the team and collaborate with colleagues to generate new program ideas
  • Contribute to the development of intellectual property
  • Mentor/lead other chemists as required


  • Ph.D. in synthetic organic, medicinal chemistry, or similar field with ≥5 years of drug discovery experience in a pharmaceutical and/or biotechnology setting with strong record of achievement
  • Strong in-depth knowledge and problem-solving skills in synthetic organic and medicinal chemistry
  • Excellent understanding of the drug discovery process and demonstrated ability to identify development candidates
  • Broad experience in hit identification (library screening, virtual screening, etc.) and hit/lead optimization
  • Good understanding of biology, pharmacology, drug metabolism and pharmacokinetics
  • Skilled at working in a dynamic multidisciplinary environment
  • Excellent verbal and written communication skills as well as strong interpersonal skills are essential

Preferred Qualifications

  • Extensive experience in working with external chemistry teams at CRO's
  • Experience in structure-based drug design and computational chemistry
  • Experience in progressing compounds from hit identification to clinical candidates

VersaPeutics, Inc. provides equal employment opportunities to all employees and applicants in all company facilities without regard to race, color, religious creed, sex, national origin, ancestry, citizenship status, pregnancy, childbirth, physical disability, mental and/or intellectual disability, age, military status or status as a Vietnam-era or special disabled veteran, marital status, registered domestic partner or civil union status, gender (including sex stereotyping and gender identity or expression), medical condition (including, but not limited to, cancer related or HIV/AIDS related), genetic information, or sexual orientation in accordance with applicable federal, state and local laws.