AbbVie

Senior Scientist I/II, Dissolution

Employer
AbbVie
Location
Lake County, IL, United States
Posted
Feb 03, 2021
Ref
2101567
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes AbbVie's diverse pipeline of innovative small molecule and therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make substantial contributions to advance AbbVie's pipeline of innovative medicines. Careers in AbbVie Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.

Role Overview

Within Analytical R&D, the Dissolution group focuses on the development of dissolution methods for pipeline and commercial products based on product & process understanding (or QbD principles), clinical relevance and regulatory requirements. The group is highly cross-functional and works closely with colleagues in Analytical R&D, Clinical Pharmacokinetics Preformulation, Formulation and Process Development, Operations and Regulatory Affairs.

Key Responsibilities
  • Representing the Dissolution group in cross-functional teams. Communicate and collaborate with cross-functional groups and departments.
  • Highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
  • Formulate conclusions and design follow-on experiments based on multidisciplinary knowledge and experimental data.
  • Analyze, interpret, and visualize data to facilitate project team decisions.
  • Author regulatory submission documentation to solicit feedback from regulators and address questions from regulators with the goal to achieve regulatory approval.
  • Regularly conceive new ideas related to dissolution, develop and secure support of research proposals, conduct and share research results. Demonstrate business impact though pipeline projects and development of more effective/efficient workflows. Present and publish results in conferences and journals.
  • Routinely demonstrate innovation and creativity in scientific research or development activities and maintain a high level of productivity in the lab.
  • Mentor and/or supervise junior scientist.
  • Interaction/collaboration with industry, academia, and regulators to learn, exchange and influence. Use the intelligence gained to recommend and implement new practices.


Qualifications

Qualifications
  • Bachelors, Masters, or Ph.D. in Pharmaceutics, Pharmaceutical Chemistry, Analytical Chemistry, or Chemical Engineeri with typically 10-12 (BS), 8-10 (MS), or 0-4 (Ph.D.) years of relevant industry experience.
  • Strong technical backgrounds in physical pharmacy, biopharmaceutics, clinically relevant dissolution method development, and excellent analytical and problem-solving skills.
  • Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
  • High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Preferred
  • Advanced degrees in Pharmaceutics, Physical Pharmacy, Pharmaceutical Chemistry, or Chemical Engineering.
  • Knowledge and/or experience in theory of mass transport, drug release principles, mathematical modelling of drug release processes for various dosage forms, drug absorption, and IVIVR/IVIVC.
  • Hands-on experiences with biopharmaceutics, dissolution method development along with fundamental understanding. Practical knowledge of various analytical techniques including bio-relevant and clinically relevant dissolution methods.
  • Knowledge of and ability to use statistical software and/or in silico modeling (e.g., GastroPlus) software.
  • Practical knowledge of regulatory requirements.

Key Leadership Competencies
  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Significant Work Activities
N/A
Travel
Yes, 10 % of the Time
Job Type
Experienced
Schedule
Full-time
Job Level Code
M
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.