Principal Scientist, Production

Employer
Bachem
Location
Torrance, CA, US
Posted
Feb 02, 2021
Ref
647436201
Hotbed
Biotech Beach
Required Education
Doctorate/PHD/MD
Position Type
Full time
The Principal Scientist in Production Department will work in a team manner to achieve goal-oriented solutions in development for optimizing and troubleshooting of production processes in Liquid Phase and/or Solid Phase-synthesis. This position will work in conjunction with the management of the production groups, will coordinate with other departments, and may lead/manage a team for assigned projects

Your Tasks:

  • Serve as subject matter expert for internal/external customers, and set clear timelines & goals for assigned projects; prioritize efforts to deliver on time; provide excellent customer experience
  • Plan and execute multiple projects in Production, and assign resources according to priorities and business requirements
  • Lead peptide and/or oligonucleotide API (active pharmaceutical ingredients) projects, including research, investigation, validation, and continuous production process improvement in Production Department
  • Timely update and report status/results of in-progress projects to the particular stakeholders; prepare technical reports; present outcome/results of projects with stakeholders
  • Maintain production quality by reducing backlog of open and aging quality records, including deviations, CAPAs, and customer commitments
  • Collaborate with cross-function departments to plan the necessary resources in order to guarantee a smooth and efficient execution of projects with optimized utilization of internal and external resources
  • Proactively monitor the trend of working techniques, purification technologies and production processes; advise and drive installation of production equipment, tools and chemical utilities
  • Support in planning and implementation of investment projects to achieve higher capacity, compliance, or new technologies; contribute to all capital expenditure activities as needed
  • Realize improvement opportunities for safety compliance and manufacturing process streamline; improve established processes with regards to cost, efficiency and safety
  • Follow good housekeeping in workplace; ensure GMP compliant operation in Production
  • Be responsible for production equipment/assets/facility; support for the related preventive maintenance
  • Support Production VP in technology transfers and business proposals
  • Recruit, coach, and supervise production staff to meet quality, quantity, and timeline requirements; identify and develop capable individuals to the first tier of supervisors (team leaders)


Required:

  • PhD Degree in Chemistry or a Science related field, 5+ years' industry experience. A postdoc experience is a plus
  • Good knowledge of peptide/oligonucleotide chemistry
  • Minimum of 10 years in Organic Synthesis and its relevant purification
  • Strong understanding of production quality systems and cGMP regulations
  • Demonstrated resourcefulness, strategic and analytical thinking, directed toward achieving objectives
  • Market-focused and customer-focused with the ability to anticipate changes in needs and potential problems
  • Excellent written and oral communication skills; outstanding interpersonal skills
  • Excellent computer knowledge, including ChemDraw, Microsoft Word, Excel, and PowerPoint. Experience of Visio and Project is a plus
  • Ability to effectively organize, multitask, and work in a fast-paced, deadline driven work environment
  • Ability to communicate in a proactive and solution-focused manner, including keeping management aware of potential issues
  • Detail oriented with the ability to troubleshoot and resolve technical and analytical problems
  • Ability to work independently and manage one's time
  • Communicate effectively and ability to function well in a team environment


Preferred:

  • Experience with Master Control and SAP
  • Industry experience
  • Understanding of GMP according to ICH Q7


Nearest Major Market: Los Angeles