Senior Scientist II/ Principal Research Scientist I, Bioinformatics Engineer

Lake County, IL, United States
Jan 30, 2021
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

The Genomics Research Center (GRC) is a center of excellence for genetics and genomics that supports both Discovery and Development. The GRC plays an integral role towards our goal of developing world class genetics and genomics research, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials. Within the GRC, the Department of Bioinformatics is responsible for data analysis and provides analytical insight for both internal and external data. This involves the identification and characterization of underlying genetic, epigenetic, or genomic factors that are associated with disease diagnosis, prognosis and response (efficacy and safety) to drug treatment, identification of new targets, and interpretation of the impact of genetic and genomic evidence from population-based studies. The scale and complexity of these projects present unique engineering challenges. To attend to these challenges, we have an exciting opportunity for a Senior Engineer, Bioinformatics, based in Lake County, IL. This candidate will manage engineers, work closely with computational biologists and research project teams to develop analytical pipelines, databases, and scientific applications for the GRC.

Key Responsibilities
  • Supervise team of 2 engineers, perform annual evaluations and support professional development.
  • Perform balancing and prioritization of engineering project work to support GRC teams.
  • Interface with Computational Biologists to optimize existing pipelines, workflows, and systems, as well as engineer new pipelines, workflows, and systems
  • Translate and implement algorithms and protocols for on-prem or cloud-based high performance computing environments
  • Support data generation core teams through process automation and data flow management
  • Develop and maintain structured data repositories for computational reassessment and record keeping with accompanying API or web-based front-end access
  • Provide sub-team personnel leadership through task and project prioritization and support
  • Interface with research-serving IT teams to assure sufficient HPC resource availability to Bioinformaticians


Position will be hired based on level of education and experience.
  • Bachelors, Masters, or PhD in Bioinformatics, Software Engineering, Computer Science, Computer and Electrical Engineering, or related field.
  • Typically at least 12+ (BS), 10+ (MS), or 4+ (PhD) years of relevant experience
  • Demonstrated experience in a supervisory role
  • Fluency in 2 or more or relevant programming languages, such as Python, Perl, R, Java, or C++
  • Experience with web application frameworks, such as RShiny, Flask, or React
  • Experience with database management technologies such as Postgres, SQL, SQLite, or MongoDB
  • Demonstrated experience versioning and documenting code with git
  • Demonstrated expertise in distributed computing, with experience in both local and cloud computing environments
  • Familiarity with standard tools and data formats related to gene expression, enrichment analysis, genetic, genomic, or epigenetic data, e.g., encountered when analyzing high-throughput transcriptomic, whole exome, whole genome, whole methylome, GWAS, or targeted resequencing data
  • Strong communication skills in a collaborative environment

Additional desired skills include:

Experience with a genomics data platform such as SevenBridges Genomics or DNAnexus

Significant Work Activities
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Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.