Head of Structural Biology

New York, NY, United States
Jan 28, 2021
Science/R&D, Biology
Pharm Country
Required Education
Position Type
Full time
We're looking to hire a Head of Structural Biology to join us in our mission to discover and develop drugs that improve human health.

Schrödinger's mission is to revolutionize drug discovery through the use of breakthrough computational methods. We are currently looking for outstanding individuals to join our drug discovery group and contribute to our rapidly expanding portfolio of drug discovery collaborations.

Our drug discovery group of over 80 scientists includes designers, modelers, computational chemists, medicinal chemists, structural biologists, biochemists, and biologists with experience working on all common target classes and therapeutic areas. We also engage with Contract Research Organizations (CRO) and Consultants in the course of our work. The group is supported by more than 100 software developers and engineers as well as a large scale compute infrastructure. Four of the programs we've worked on in the past 7 years have progressed into the clinic; three are still progressing through trials and one is approved by the FDA.

Who will love this job:
  • A passionate and highly motivated structural biologist with a strong understanding of all aspects of their field, including construct design, protein production and purification, protein crystallization, X-ray crystallography, cryo-EM, and structural refinement techniques
  • An innovative scientist who enjoys being at the forefront of the latest technological advancements and scientific developments for structural determination of proteins, antibodies and protein-ligand complexes
  • An experienced team leader in the field with a proven track record of driving teams - both on-site as well as remote - in the pursuit of challenging, previously uncharacterized structures

What you'll do:
  • Oversee the expansion of our structural biology capabilities by working with both internal scientists as well as CROs around the world
  • Drive the structural determination of novel, previously unsolved protein structures for the enablement of new drug discovery programs
  • Participate in the identification and characterization of new potential targets for drug discovery, and assess their amenability to structural determination
  • Work with a large multi-disciplinary team to ensure that our drug discovery programs are structurally-enabled and well-supported all the way to the clinic

What you should have:
  • A PhD in Structural Biology, with a focus on the use of X-ray crystallography and/or cryo-EM for the determination of protein and protein-ligand complexes
  • 10+ years of experience as head of a structural biology team in a pharmaceutical or biotechnology setting, supporting a diverse array of drug discovery programs
  • A proven track record of devising strategies for the structural determination of highly challenging targets, using a variety of technologies and approaches
  • Experience working with structural biology CROs, and extensive familiarity with their capabilities

Pay and perks:

Schrödinger understands it's people that make a company great. Because of this, we're prepared to offer a competitive salary, stock options, and a wide range of benefits that include healthcare (with dental and vision), a 401k, pre-tax commuter benefits, a flexible work schedule, and a parental leave program. We have catered meals in the office every day, a company culture that is relaxed but engaged, and over a month of paid vacation time. Our Administrative and Human Resources departments also plan a myriad of fun company-wide events. New York is home to our largest office, but we have teams all over the world. Schrödinger is honored to have been selected as one of Crain's New York Best Places to Work for the past three years running.

Sound exciting? Apply today and join us!

As an equal opportunity employer, Schrödinger hires outstanding individuals into every position in the company. People who work with us have a high degree of engagement, a commitment to working effectively in teams, and a passion for the company's mission. We place the highest value on creating a safe environment where our employees can grow and contribute, and refuse to discriminate on the basis of race, color, religious belief, sex, age, disability, national origin, alienage or citizenship status, marital status, partnership status, caregiver status, sexual and reproductive health decisions, gender identity or expression, or sexual orientation. To us, "diversity" isn't just a buzzword, but an important element of our core principles and key business practices. We believe that diverse companies innovate better and think more creatively than homogenous ones because they take into account a wide range of viewpoints. For us, greater diversity doesn't mean better headlines or public images - it means increased adaptability and profitability.