Skip to main content

This job has expired

You will need to login before you can apply for a job.

Sr. Research Associate, Analytical Development

Employer
Omeros Corporation
Location
Seattle
Start date
Jan 15, 2021

View more

Job Details

Research Associate II/Sr. Research Associate, Analytical Development

This position will support clinical development and commercialization of antibody therapeutics. The Research Associate will bring a strong technical background including development, transfer, and qualification of analytical methods, characterizing physicochemical attributes of therapeutic candidates, developing new and orthogonal methods for extended characterization, and evaluating orthogonal and complimentary technologies to improve throughput. This position will also contribute to tech transfer to clinical and commercial stage CRO's/CMO's and may contribute to managing external CRO's who may develop and implement methods for routine testing and extended characterization.

Good things are happening at Omeros!

Come join our Omeros CMC Team!

Who is Omeros?

Omeros is a commercial-stage biopharmaceutical company committed to discovering, developing and commercializing small-molecule and protein therapeutics for large-market and orphan indications targeting inflammation, complement-mediated diseases, disorders of the central nervous system and immune-related diseases, including cancers. In addition to its commercial product OMIDRIA (phenylephrine and ketorolac intraocular solution) 1%/0.3%, Omeros has multiple phase 3 and phase 2 clinical-stage development programs focused on complement-mediated disorders and substance abuse. Omeros also has a diverse group of preclinical programs including GPR174, a novel target in immuno-oncology that modulates a new cancer immunity axis recently discovered by Omeros. Small-molecule inhibitors of GPR174 are part of Omeros' proprietary G proteincoupled receptor (GPCR) platform through which it controls 54 new GPCR drug targets and their corresponding compounds. The company also exclusively possesses a novel antibody-generating platform.

What are your job responsibilities?

  • Analytical method development, testing, transfer, qualification, and validation in a GLP and/or GMP environment
  • Troubleshoot typical method and equipment challenges
  • Write standard test methods, technical reports summarizing analytical data, and qualification / validation reports
  • Participate in cross-functional teams as a representative of the Analytical Development group
  • Assists in trouble-shooting CMC-related problems from CROs / CMOs
  • Assists in investigations involving data generated internally and by CROs / CMOs
  • Ensures laboratory equipment is calibrated and maintained in proper working order to enable compliance with GLP and/or GMP environments
  • Contribute to drafting regulatory submissions
  • Ensures compliance with all applicable regulatory guidelines
What education and experience do you need?

  • BS or MS degree in Chemistry, Biochemistry, Biology, Analytical Chemistry, or a related field with a minimum of 5 years of biotechnology and/or pharmaceutical industry experience
  • Experience developing robust HPLC (SEC, RP, peptide map, CEX, etc.) and/or CE-based (CE-SDS, cIEF, icIEF) methods
  • Experience with troubleshooting and optimizing methods
  • Experience with routine lab equipment and methods, including preparing buffers, measuring pH, UV absorbance, quantifying particulates, etc.
  • Strong understanding of technical principles of chromatographic and/or electrophoretic methods
  • Capable of interpreting data and communicating and presenting results to peers and management
  • Demonstrated written and verbal communication skills with peers and management
  • Experience and proficiency with Waters Empower and/or Sciex 32 Karat software is highly desired
  • Experience with technology transfer to third parties is desired
Behavioral Competencies:

  • Demonstrated ability to build and maintain positive and collaborative relationships across functional areas and with management
  • Must display strong analytical, problem-solving, and multi-tasking capabilities
  • Detail oriented, proactive, and self-motivated
Physical Demands Required:

  • Intermittent physical activity including bending, reaching, pushing, pulling, or lifting up to 40 lbs.
  • May encounter prolonged periods of sitting
  • This position requires working with and near hazardous material
If you have the experience, skills and knowledge we are seeking, we'd love to hear from you! This is an exciting opportunity for the right person!

Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to hr@omeros.com or contact Omeros, asking for Human Resources, at (206) 676-5000

Company

At Omeros, we are proud of our innovative and cutting-edge science. Our world-class team has achieved scientific advances that no other group has been able to accomplish, delivering wholly new classes of therapeutics to benefit patients. We let science lead the way.

From our foundation of groundbreaking science, we continue to build and advance a deep and diverse pipeline of small-molecule and protein therapeutics. We are not interested in developing “me-too” products; instead, we are focused on tackling challenging diseases and disorders with significant unmet medical needs. The result is an exciting pipeline of first-in-class drugs with new mechanisms of action that target previously untapped receptors and enzymes.

The Omeros team is exceptionally talented, passionate, collaborative and diverse. We hire smart, creative and hard-working people who want to play a meaningful part in building a preeminent biopharmaceutical company. We come from all corners of the globe, bringing unique abilities and experiences together to provide hope to patients and their families.

Company info
Website
Phone
206.676.5000
Location
201 Elliott Avenue West
Seattle
Washington
98119
US

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert