In Vivo Research Associate/Senior Research Associate

South San Francisco, California
Jan 11, 2021
Required Education
Bachelors Degree
Position Type
Full time

Position Overview

E-scape Bio Inc. is a clinical stage, Precision Neurology biopharmaceutical company focused on the discovery and development of therapies to treat genetically defined, neurodegenerative diseases. We are seeking a highly motivated individual to support a drug development team in our organization. The individual will primarily be responsible for in vivo workstreams but will have a significant share of laboratory benchwork in support of drug development efforts. This individual will have a clear understanding of design and execution of in vivo neuro efficacy studies. The individual will demonstrate enthusiasm for, and a desire to learn about, the cause and cure of neurodegenerative disorders.

Key Responsibilities

  • Organize and prepare animal cohorts for experimental procedures- Breeding, study enrollment
  • Perform daily formulation and administration of substances in support of drug discovery efforts (OG, IP, SC, IV)
  • Perform animal behavioral assays- Behavioral Battery, experience with Ethovision XT and Erasmus Ladder a plus
  • Colony management of multiple transgenic lines including breeding, tagging, weaning and genotyping
  • Perform in vivo experimental procedures including tissue collection and processing, live sampling
  • Perform molecular biology techniques such as PCR, immunoassays and tissue culture
  • Adhere to safety policies, departmental SOPs, animal welfare guidelines and perform documentation for IAUCUC Protocols
  • Work cross-functionally with multiple teams within the organization to achieve goals
  • Maintain and complete documentation of all study procedures and data in an electronic laboratory notebook (ELN) and/or other animal tracking software
  • Share weekend and holiday hours with peers on a rotational basis


  • BS or MS in life sciences with 4+ years in vivo experience; AALAS cert a plus
  • Organized and disciplined with proficiency in Microsoft Office and Prism; experience with laboratory animal tracking software
  • Experience with Survival Surgery techniques and Histology will be a plus
  • Must be able to provide and follow verbal and written instructions and exhibit interpersonal skills that are conducive to effective communication and teamwork.  
  • The candidate will be a highly motivated and reliable individual with demonstrated capacity to learn and perform with precision