Research Associate, Mammalian Cell Culture Technology

Ambrx, Inc.
La Jolla, CA, United States
Jan 06, 2021
Science/R&D, Research
Biotech Beach
Required Education
Associate Degree
Position Type
Full time
Ambrx Inc., is a clinical-stage biopharmaceutical company focused on developing Precision Biologics using an expanded genetic code. Ambrx technology uses an expanded genetic code to incorporate synthetic amino acids into protein, all completed within a living cell. These synthetic amino acids enable the creation of Precision Biologics, an exciting new class of therapeutics with broad application and potential. This includes next-generation antibody drug conjugates (ADCs), bispecifics, and targeted immuno-oncology therapies for cancer as well as smart cytokines to modulate the immune system, and long-acting therapeutic peptides for metabolic and cardiovascular disease.

• Work in the cell line development (CLD) group to optimize CLD process to further improve efficiency and shorten timeline
• Improve transient expression titer of mAb or other therapeutic proteins to quickly provide gram of material for discovery projects
• Collaborate seamlessly with cell culture group to deliver production cell lines for GMP manufacturing and to develope platform batch/fed batch cell culture process

• Cell Biologist or Molecular Biologist with an MS degree with 1-3 years of experience, or BS with 4-7 years of experience, in the biotech and/or pharmaceutical industry
• Expertise in recombinant protein expression in a wide variety of systems (bacterial, mammalian cell lines)
• Knowledge and hands-on experience in general molecular biology, especially in cloning, PCR, and vector construction
• Excellent hands-on skills in aseptic tissue culture, ELISA, HPLC, Octet
• Working experience in cell culture ranging from microplates, deep-well plates to shake
flask is required
• Skills in operation and maintenance of cell imager, cell counter is a plus
• Demonstrated passion to learn and advance new technology
• The ability to succeed in a multidisciplinary and dynamic team environment.
• Independent thinking and team player
• Good communication and strong problem-solving skills
To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed.
Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits.