Research Associate II-III, In Vivo Models

Durham, NC, United States
Jan 06, 2021
Science/R&D, Research
Bio NC
Required Education
Bachelors Degree
Position Type
Full time
The Research Associate II-III will work within the Animal Studies team and carry out In Vivo studies to support research efforts in accordance with Precisions goals. Responsibilities include rodent handling, colony management, dosing and management of studies.

Essential Duties and Responsibilities

Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions of this position. This list contains the major duties and requirements of the job and is not all-inclusive. Incumbent(s) may be expected to perform role-related duties other than those contained in this document.
  • Basic handling, observation, identification and handling of rodents
  • Perform laboratory experiments including sample preparation, and data collection using established protocols
  • Colony management
  • Perform routine preparation/monitoring of laboratory materials, maintain equipment and order supplies
  • Laboratory cleaning and sanitization
  • Perform euthanasia as necessary
  • Administer intravenous, intraperitoneal, intramuscular, retro-orbital and subcutaneous treatments
  • Place rat catheters, administer mammary fat pad and sub-mental injections
  • Study plan management and independent execution
  • Tissue harvest, and tail biopsies for laboratory analysis and/or monitor general post-operative condition as directed
  • Blood collection and blood chemistry analysis
  • Image both immune-competent and immunocompromised animals using the IVIS Spectrum and analysis of data utilizing Living Image acquisition software
  • Data compilation and implantation to electronic notebook (ELN)
  • Cardiac perfusion and organ harvest
  • Other duties related to team and job functions as requested by manager


The requirements listed below are representative of the knowledge, skill, and/or ability required to perform this job successfully.

Education/ Experience:
  • Successful candidate should have a BS in life sciences and 2+ years of related experience; or equivalent combination of education and experience

  • Comfortable with animal handling and restraint
  • Experienced in intravenous, intraperitoneal and retro-orbital injection
  • Ability to work with hazardous chemicals and knowledge of safety requirements to provide instructions and recognize and correct hazardous conditions
  • Ability to establish and maintain positive relationships with employees, vendors and external agencies
  • Ability to identify and resolve problems as well as communicate clearly and concisely
  • Ability to work successfully both independently and in a collaborative environment
  • Ability to handle multiple tasks and prioritize effectively
  • Willingness to assist the team with occasional night/weekend work if needed

  • Experience with immunodeficient animals
  • Experience with Living Image and GraphPad Prism
  • Experience with orthotopic routes of administration

  • This is an office-based position located out of Precision BioSciences main campus in Durham, NC

Travel Requirements
  • This position requires up to 50% local travel between Precision BioSciences main campus and animal facility. The Research Associate will be expected to travel to all applicable locations when needed

Precision BioSciences, Inc. (Nasdaq: DTIL), is a clinical stage biotechnology company dedicated to improving life (DTIL) with its novel and proprietary ARCUS genome editing platform. This isnt just a statement supporting the products that were developing its a statement that speaks to our collective desire to do our part in improving the lives of those around us. ARCUS is a highly specific and versatile genome editing platform designed with therapeutic safety, delivery, and control in mind. Using ARCUS, Precision is developing allogeneic CAR T and in vivo gene correction therapies for cancer and genetic diseases. Our team includes pioneers in genome editing, leaders in business, and a full staff of talented and committed people who are excited to be a part of medical and scientific breakthroughs. For additional information, please visit www.

Precision BioSciences actively fosters an inclusive environment to ensure we attract and retain the best talent; we value diversity of life experiences and perspectives; and we encourage innovation in pursuit of our mission. We provide equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, disability, genetic information, marital status, amnesty, or status as a covered veteran in accordance with applicable federal, state and local laws. Precision BioSciences complies with applicable state and local laws governing non-discrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including, but not limited to, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation, and training.