Senior/Principal Scientist, DNA Damage Response 高级/资深科学家
- Employer
- Zai Lab (US) LLC
- Location
- San Francisco, CA, United States
- Start date
- Jan 4, 2021
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- Discipline
- Science/R&D, Biotechnology
- Required Education
- Doctorate/PHD/MD
- Position Type
- Full time
- Hotbed
- Biotech Bay
Job Details
To lead biology efforts for projects in the area of DNA damage response. This team will play a critical role in target validation/the drug discovery and development process to ensure delivery of high-quality small molecule compounds with well-characterized mechanism of action.
Organizational Relationships:
Reports to the Head of Discovery Biology and Translational Medicine. This position requires extensive collaboration with Medicinal Chemistry, In vivo Pharmacology and DMPK
Resources Managed:
Oversight of direct reports and outsourcing activities
Primary Duties:
- Oversee activities in support of target validation/early drug discovery projects
- Contribute to define screening funnel for drug discovery projects
- Direct studies aimed at characterizing mechanism of action of lead small molecules
- Manage internal and external (academic and contract research organizations) resources to deliver quality data in an efficient manner
- Contribute to building a culture that embraces continuous learning and improvement, increasing technical skill base and disease biology expertise; take a proactive role in personal growth and scientific development
Qualifications & Prior Experience:
- PhD in Biochemistry or Cellular & Molecular Biology with an educational focus in cancer research and DNA damage response
- At least 3 years for Senior or 5 years for Principal Scientist role of experience in academia and/or pharmaceutical industry
- Strong understanding of key components and process of drug discovery
- Expert in biochemical assays, cell-based assays, RNAi and methodologies to support structure-activity relationship and target validation
- Demonstrated ability to work independently and supervise direct reports
- Strong communication skills and ability to work effectively in a multidisciplinary team environment
- Proven track record of productivity, as evidenced by driving projects forward and robust publications
Please send your resume to talent_us@zailaboratory.com
Company
Zai Lab is an innovative commercial stage biopharmaceutical company focused on bringing transformative medicines for cancer, infectious and autoimmune diseases to patients in China and around the world. To quickly target the large, fast-growing segments of China’s pharmaceutical market and address unmet medical needs, Zai Lab’s experienced team has secured partnerships with leading global biopharma companies, generating a broad pipeline of innovative drug candidates. Zai Lab has also built an in-house team with strong drug discovery and translational research capabilities, aiming to establish a global pipeline of proprietary drug candidates against targets in our focus areas. Zai Lab’s vision is to become a fully integrated biopharmaceutical company, discovering, developing, manufacturing and commercializing its portfolio in order to impact human health worldwide.
For additional information about the company, please visit www.zailaboratory.com.
Stock Symbol: ZLAB
Stock Exchange: NYSE
- Website
- http://www.zailaboratory.com/
- Phone
- 650-449-8674
- Location
-
1440 O’Brien Drive
Menlo Park
CA
94025
US
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