Senior Research Associate, Analytical Development - BioAssay

Overview

Ready to join a team committed to developing and commercializing gene therapies for patients and families devastated by rare neurological genetic diseases? Since 2013, Novartis Gene Therapies (formerly AveXis) has had one focus: bringing change to those devastated by genetic diseases.

The Novartis Gene Therapies culture embraces this mission. As a compassionate and dedicated team, we are enthusiastic about the science behind our work and finding answers to difficult questions. We are dedicated to communities affected by rare diseases, and these patients and families are the motivation for everything we do.

We have built a team with exceptional depth of experience, unified by a common vision; to develop gene therapies with the potential to positively impact the lives of the patients and families devastated by rare and life-threatening neurological genetic diseases. Though we are proud of what we have achieved to date, we remain relentlessly focused on making that vision a reality.

The Senior Research Associate, Analytical Development - BioAssay, performs routine testing and to develop Bioassays suitable for lot disposition and characterization of gene therapy drug products and substances.

Responsibilities

• Performs a wide variety of laboratory tasks and experiments.
• May make detailed observations, analyze data and interpret results.
• Maintains laboratory equipment and inventory levels for laboratory supplies.
• May write experimental reports, summaries and protocols.
• May also be responsible for media and critical solution preparation in the research and development area, including experiments as required and outlined.
• May also develop and maintain record keeping for experiments performed.
• Performs limited troubleshooting and calibration of instruments.
• Under supervision, develop, optimize and qualify Bioassays suitable for gene therapy characterization, lot release and stability monitoring, may participate in assay transfer to QC department
• Performs routine sample testing and data analysis with existing analytical methods in support of regulatory filings and manufacturing process development and validation
• Identifies lab needs/improvements and provides suggestions
• Other related job duties as assigned.

Qualifications

• Bachelor's degree in Biology, Biochemistry, Bioengineering or related scientific discipline with 4 years research experience in area or 7 years of equivalent education/experience may be accepted.
• Clear understanding and working knowledge of Cell Biology, protein and DNA chemistry.
• Clear understanding and working experience with cell-based assays as well as other plate-based assays using variety of platforms including but not limited to ELISA, MSD, high-content imaging and luminescent/fluorescent plate reader.
• Quick learner, highly motivated, hard-working and detail oriented. Strong ability to work in a fast-paced team environment with highly goal-oriented approaches and to prioritize work from multiple projects with can-do attitude is required.
• Excellent written and verbal communication skills.

The level of this position will be based on the final candidate's qualifications.

Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice.

Novartis Gene Therapies is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity, national origin, genetics, disability, age, sexual orientation or veteran status.

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