Scientist I/II - Formulation & Delivery

Employer
CSL Behring
Location
Cambridge, Massachusetts
Posted
Dec 22, 2020
Ref
R-127907
Required Education
Bachelors Degree
Position Type
Full time
About CSL

With operations in 35+ nations and ~27,000 employees worldwide, CSL is driven to develop and deliver a broad range of lifesaving therapies to treat disorders such as hemophilia and primary immune deficiencies, and vaccines to prevent influenza. Our therapies are also used in cardiac surgery, organ transplantation and burn treatment.

CSL is the parent company of CSL Behring and Seqirus. CSL Behring is a global leader in the protein biotherapeutics industry, focused on bringing to market biotherapies used to treat serious and often rare conditions. CSL Behring operates CSL Plasma, one of the world's largest collectors of human plasma, which is used to create CSL's therapies. Seqirus is one of the largest influenza vaccine companies in the world and is a transcontinental partner in pandemic preparedness and a major contributor to the prevention and control of influenza globally.

We invite you to take a look at the many career possibilities available around the globe and consider building your promising future at CSL by becoming a member of our team!

Job Description

This position is a responsible for performance of mRNA vaccine and adjuvanted protein vaccine formulation and characterization, to support vaccine discovery and development.

Responsibilities:
  • Develop the lyophilization formulation and other dry formulation for mRNA vaccines.
  • Develop mRNA vaccine formulation process, biophysical characterization and functional assays to support vaccine formulation development.
  • Write experimental protocols and prepare internal reports. Maintain lab notebooks.
  • Maintain functional laboratory equipment and follow HSE regulation.


Qualifications:
  • BS degree with 5+ years experience, MS with 3+ years experience or PhD
  • Experience with lyophilization for lipid nanoparticle formulation or other biologics is required.
  • Experience with lipid nanoparticle formulation or other biologics formulation is required.
  • Experience with nanoparticle characterization eg. DLS, MALS, DSC and HPLC is required.
  • Experience with cell-based assay is preferred.
  • T he ability to generate accurate and reproducible results along with multi-tasking and working effectively in a fast-paced environment are required.
  • Ability to work in teams and written/oral communication skills are required.
  • Excellent communication and presentation skills (English language).


* Level will be determined based on level of experience and expertise