Senior Associate Scientist - Protein Technologies

South San Francisco, CA, US
Dec 20, 2020
Required Education
Bachelors Degree
Position Type
Full time
Amgen's Therapeutic Discovery organization is seeking a collaborative Senior Associate Scientist to join the Protein Technologies group at our South San Francisco site. Protein Technologies is responsible for designing, planning and executing on the generation of key enabling reagents to support early discovery of small and large molecule therapeutics and ground-breaking modalities.

The Senior Associate Scientist will be a part of a multidisciplinary team with capabilities in molecular engineering, cloning, expression and purification of proteins, including antibodies, bispecifics and membrane proteins. The ideal candidate will have broad laboratory training, deep scientific curiosity and a positive approach to working in a team-based research environment along with a track record of creative problem-solving and enthusiasm for taking on difficult research challenges.

Basic Qualifications

Master's degree and 3 years of related scientific experience
Bachelor's degree and 5 years of related scientific experience

Preferred Qualifications
  • Proven microbiology skills culturing E. coli and yeast
  • Working knowledge of bioreactor fermentation
  • Experience with in vitro protein refolding, refolding screens, scale-ups
  • Detailed knowledge in recombinant protein purification (including affinity, ion exchange, HIC, SEC) and methods development
  • Biochemistry analytical experience (SDS PAGE, Western Blot, HPLC, Mass Spectrometry)
  • Familiarity with chromatography hardware and software (GE AKTA, Agilent HPLC)
  • Strong written/verbal communication and interpersonal skills
  • Demonstrated scientific analysis and problem-solving skills as evidenced in peer review publications.
  • Desire to be a team player in a dynamic, cross-functional environment

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.