Senior Research Associate, Viral Vector Process Development

South San Francisco, California, United States
Dec 19, 2020
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
Thank you for your interest in a career at Senti Biosciences. We are passionate about developing cell therapies with the ability to outsmart cancer and other complex diseases. We find purpose and meaning in knowing that our efforts will soon improve the lives of patients and their families. With science as our foundation and empathy as our key guiding principle, colleagues become friends, managers become mentors, and with time, cancer becomes history.

Senti Bio is seeking a team-oriented Scientist or Chemical Engineer to join Senti Bio's viral vector core to support process development of novel cell and gene therapies. A successful applicant will be able to generate multiple viral vector preparations, design and execute experiments, and work collaboratively to construct solutions to development roadblocks. Applicants should have current knowledge of molecular, viral and cell biology, protein

production, and purification techniques.

    • Viral vector manufacturing of gene circuit construct candidates using Senti Bio's proprietary production platform.
    • Design processes and execute experiments to improve overall system performance.
    • Analyze and present data at cross-team functional meetings.
    • Communicate design ideas and translate relevant information into process improvements.
    • Work with the viral vector team to develop a process for larger scale virus production for pre-clinical development
    • Perform routine cell culture maintenance, cell counting, as well as media and buffer formulation.
    • Routinely enter data into electronic lab notebook system and worksheets.

    • Bachelor's degree in a related scientific or technical field.
    • 3+ years of experience in a laboratory setting working with viral vectors
    • Hands-on proficiency with retroviral vector production, suspension fermentation, and/or protein purification preferred
    • Some experience with downstream processing is a plus
    • Viral vector manufacturing experience in a GMP setting is a plus
    • Team player, proactive and willing to work in a small team environment.
    • Proficient with MS office and other commonly used software and technology platforms.
    • Self-motivated and eager to take on temporary responsibilities outside of the initial job description to support the team

Salary and Benefits
    • Competitive compensation package and title commensurate with qualifications and experience in the South San Francisco Biotech market.
    • Significant growth opportunity as the company expands.

Senti Bio is the next generation therapeutics company that designs gene circuits and programs cells for tremendous therapeutic value. Our mission is to engineer an entirely new class of medicine that will transform people's lives by curing the most challenging diseases. We are proud to count NEA, 8VC, Amgen Ventures, Pear Ventures, Lux Capital, Menlo Ventures, Allen & Company, Nest.Bio , Omega Funds, Goodman Capital, and LifeForce Capital among our investors. Senti Bio is based in South San Francisco, CA, USA.