Scientist I (Biochemistry)

Employer
CSL Behring
Location
Cambridge, Massachusetts
Posted
Dec 18, 2020
Ref
R-127576
Required Education
Bachelors Degree
Position Type
Full time
About CSL

With operations in 35+ nations and ~27,000 employees worldwide, CSL is driven to develop and deliver a broad range of lifesaving therapies to treat disorders such as hemophilia and primary immune deficiencies, and vaccines to prevent influenza. Our therapies are also used in cardiac surgery, organ transplantation and burn treatment.

CSL is the parent company of CSL Behring and Seqirus. CSL Behring is a global leader in the protein biotherapeutics industry, focused on bringing to market biotherapies used to treat serious and often rare conditions. CSL Behring operates CSL Plasma, one of the world's largest collectors of human plasma, which is used to create CSL's therapies. Seqirus is one of the largest influenza vaccine companies in the world and is a transcontinental partner in pandemic preparedness and a major contributor to the prevention and control of influenza globally.

We invite you to take a look at the many career possibilities available around the globe and consider building your promising future at CSL by becoming a member of our team!

Job Description

Job Summary:

This position is responsible to conduct variety of biophysical/chemical methods for protein/mRNA characterization to support assay development, and QC studies on potential vaccine candidates. The ideal candidate would help maintain the analytical lab instruments to support characterization studies.

Major Responsibilities:

Conduct biophysical/chemical methods for protein characterization
  • Conduct biophysical assays to characterize protein-protein interactions to evaluate potential vaccine candidates
  • Perform and optimize MS-based methods for biomolecules quantification to support stability studies
  • Perform quality control studies for proteins by variety of analytical methods to discover potential bioassays for product development
  • Document and optimize protocols for protein-based assays and analytical instruments to help maintain the analytical lab


Documentation and presentation of scientific results.
  • Write experimental protocols and prepare internal reports. Maintain lab notebooks.
  • Collaborate with project teams, present research results and contribute to technical advancements and publications.


Lab management.
  • Maintain functional laboratory equipment and follow HSE regulation.


Other job duties that may be assigned from time to time.
  • Support other functions and other divisions when needed.

Minimum Qualifications:
  • B.S. or Master's degree in Biochemistry/bio/chemical engineering or related biological sciences.
  • B.S. with 3+ years, or M.S. with 0-1+ years of academic or pharmaceutical/biotech experience in biochemistry, preferably laboratory experience with training in a relevant technical discipline eg. molecular and cellular biology, analytical biochemistry etc.
  • Hands on experience with proteins/mRNA and biological samples is required
  • Experience with analytical techniques such as LCMS, WB, HPLC, DSC, SPR, DLS, SEC-MALS, and fluorometry is preferred.
  • The ability to generate accurate and reproducible results along with multi-tasking are critical.
  • Desire to work under a collaborative and fast pace environment is preferred.
  • Organizational, written and oral communication skills and ability to work in teams is required.