Intern - Drug Metabolism

Location
Foster City, CA, United States
Posted
Dec 16, 2020
Ref
2102261
Required Education
Bachelors Degree
Position Type
Full time
Intern - Drug Metabolism
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company’s five core values. That’s because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible


A summer research internship is available in the Drug Metabolism Department of Gilead Sciences, Foster City. The internship project will focus on the application of cellular and bioanalytical assays to evaluate biliary efflux in hepatocytes. The candidate will utilize primary hepatocyte-based cellular assays and appropriate molecular biology, and highly sensitive LC-MS bioanalytical methods to quantify the effects that bile acids have on biliary efflux. They will be responsible for characterizing the effects of bile acids on transporters in 2D and 3D hepatocyte cultures using gene and expression assays and immuno-cell labeling.

Working with supervision, the candidate will execute assigned experiments that support research activities and project goals. With guidance and direction they will be involved in development of new assays, planning experiments, and selecting appropriate reagents and controls. The candidate will participate in group meetings and may be expected to present the results of their work, interpret data, and draw conclusions.

Knowledge, Experience and Skills
The candidate should have completed at least 2 years of undergraduate coursework and have a solid foundation in molecular biology, immunology and organic chemistry. Prior coursework or knowledge in the field of molecular biology including PCR, qRT-PCR, western blots, and immunoassays, cell biology including eukaryotic cell culture, and bioanalytical techniques such as mass spectroscopy and chromatography is highly desirable. The candidate should be highly self-motivated with an interest in translational biology and drug development, and is expected to commit a minimum of 12 weeks to this project. Microsoft office computer experience and familiarity with basic laboratory equipment such as pipetting, aseptic technique, cell culture, and spectrophotometry is highly preferred. Strong communication and interpersonal skills are required.

For jobs in the United States:

As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the ‘EEO is the Law' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.