Associate Scientist, Disease Biology

Our Mission: Developing curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

At Intellia, we are committed to solving the complex challenges of making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to create novel engineered cell therapies for immuno-oncological and autoimmune diseases.

Job Description:

Intellia is seeking a highly skilled and motivated Senior Research Associate/ Associate Scientist to join our growing team. The primary responsibility for this position will be to assist with in vitro experiments in primary cells and cell lines as well as in vivo assays focused on the development of gene editing therapies. We are looking for an experienced junior scientist to help us to execute on Intellia's gene editing programs. The candidate will be involved in the design, execution, and interpretation of experiments, and will interface regularly with our collaboration partners.

Responsibilities:

• Help to optimize new protocols for engineering primary and established cell lines using both viral and non-viral vectors
• Help optimize molecular biology detection and quantification techniques, such as Western blots, ddPCR, ELISA
• Conduct experiments independently and in collaboration with team colleagues
• Maintain highly detailed, up-to-date records of all experiements conducted
• Communicate research and development findings with internal and external partners

Required skills:

• Bachelor's Degree in biological sciences
• Experience with liver diseases, hematologic diseases, nervous system diseases
• Solid foundation in primary cell culture
• Solid foundation in molecular biology skills (Western blot, PCR, pull down)
• Well-organized and capable of multitasking with complex, overlapping experiments
• Demonstrated ability to think critically and creatively to solve scientific problems
• Collaborative nature and flexibility to pitch in and help team members to deliver on commitments
• Strong desire to learn new skills and biology related to new therapeutic areas
• Excellent time management, communication and presentation skills
• Working knowledge of CRISPR/Cas9 gene editing
• Proficiency with sample preparation for NGS
• Experience using viruses (AAV or other) in mammalian cells
• Proficiency with processing of mouse tissues
• In vivo experience with mouse models, and/or willingness to learn
• Expertise in flow cytometry and FACS

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EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.