Scientist - Protein Biophysical Characterization

Irvine, CA, United States
Nov 25, 2020
Required Education
Bachelors Degree
Position Type
Full time
Envision working with energetic colleagues and inspirational leaders. Now, place yourself in that mix; leading discussions, asking the right questions and driving results.

What Your New Manager Wants You To Know

"I'm looking for a talented team player to contribute to a dynamic, innovative, and matrixed Discovery organization. If you are interested in knowledge of protein biophysical characterization to the screening and development of novel protein therapeutics, I would be very interested in receiving your resume. Let's discuss what you can bring to the team and what you aspire to do in the future."

Allergan Aesthetics R&D, Biological Research is seeking a highly motivated and innovative candidate for the role of Scientist, Protein Biophysical Characterization. The successful candidate for this position will work independently and contribute expertise to projects aimed at characterizing protein-based therapeutics. He/she will have a critical role in developing and conducting protein characterization strategies to select, optimize, and prioritize, therapeutic protein candidates for development. Expertise in the characterization of in vitro and cellular protein-ligand binding, as well as evaluating protein folding and stability of biologicals are a requisite. This individual will organize, analyze and interpret results, come forward with recommendations or understanding of the results, and communicate and present in team meetings and reports. The ideal candidate will be able to propose and design characterization strategies and have exceptional troubleshooting skills. Excellent communication skills and the ability seamlessly work with diverse teams to address scientific challenges on defined timelines is critical.

Knowledge and experience with surface plasmon resonance (SPR), dynamic light scattering (DLS), differential scanning fluorimetry (DSF), circular dichroism (CD), intrinsic fluorescence, size-exclusion chromatography with multi-angle light scattering are required (SEC-MALS). Experience with HPLC, UPLC, and protein expression and purification are required. Experience with cell biology and/or protein/cell interactions is desired.

The position is on the scientific track at Allergan working on complex assigned research projects. Taking input from management and/or the lead of matrixed projects, the candidate will be responsible for designing and conducting experiments to meet the needs of the program and project teams. The individual will also be responsible for interpreting the results and reporting back to management and project teams in the form of verbal presentation, slides, and written reports.

Furthermore, the position requires the individual to work with and in areas requiring select agents and Toxins access (i.e. Biosafety level 2 and biosafety level 3 laboratories). Access to and use of select agents is regulated by federal policies. Therefore, the candidate must conduct all work activities in compliance with AbbVie internal and applicable regulatory requirements. AbbVie internal requirements include compliance with ethics, environmental health and safety, financial, human resources, and general business policies, requirements and objectives.

YOU ARE more than just a title, YOU ARE...

First class team player : collaborate across multiple disciplines to ensure compliance and ability to influence cross-functional teams and senior leadership.

You Will
  • Independently design and conduct complex experiments to address specific protein characteristics in a manner that reliable results are achieved in a timely manner.
  • Document and interpret results in order to reach conclusions, discuss with supervisor and/or team leader to map subsequent experiments.
  • Develop and maintain up-to-date knowledge and skill base by reviewing the literature, attending seminars and meetings.
  • Prepare technical reports, presentations, and appropriate documentation of work performed. Assist supervisor in maintaining project documentation. Attend and participate in lab, team and departmental meetings. Present data as required.



You Bring
  • Bachelor of Science with 7 - 9 years of experience or Master of Science with 4 - 6 years of experience or Doctorate Degree with 0 - 2 years of experience.

In this role, we're looking for a leader who will :
  • Act as an Owner
  • Be Excellence Focused
  • Act as an Influencer

Yes, 10 % of the Time

Job Type


Equal Employment Opportunity
At Allergan, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.