Manager, Neuroscience & Ophthalmology Genetics

Tarrytown, NY, United States
Nov 24, 2020
Required Education
Position Type
Full time
The Manager, Therapeutic Area Genetics - Neuroscience & Ophthalmology will take on responsibilities for the design, execution, and interpretation of genetics studies focusing on neurological diseases. The goals of the team is to apply genetics to target discovery, selecting indications for drug programs, and patient/disease stratification through genetic analyses.

As a Manager, Therapeutic Area Genetics, a typical day might look like:
  • Leading genetics discovery projects, supporting new programs/collaborations, and supporting the execution of overall scientific strategy in neurological disease genetics.
  • Partnering with multidisciplinary genetics team consisting of human genetics scientists, bioinformaticians, statistical geneticists, and others to craft, execute, and interpret genetics studies related to neurological diseases for the center. Collaborate with external partners and internal Regeneron scientists in such efforts.
  • Working with research and clinical colleagues at Regeneron to introduce human genetics evidence and studies into current research plans and to support drug development efforts.
  • Providing human genetics expertise and insight on projects within other R&D departments at Regeneron including therapeutic focus area teams in Neuroscience, precision medicine, and early and late clinical development.
  • Surveying the literature and conferences for discoveries and findings from the broader genetics' community. Integrate such findings into study opportunities and considerations internally.
  • Communicating and reporting study findings and analyses with leadership, administration, and collaborators.

  • You have proven track record to craft and lead human genetics studies delivering novel genetic findings and medically relevant gene discoveries in a team based environment.
  • You are a motivated teammate with a desire to pursue genetic discovery in a results oriented, multi-disciplinary environment.
  • Familiarity with statistical genetics and experience leading a breadth of study designs and analyses spanning family and Mendelian studies, population genotype-phenotype association studies, etc.

To be considered for this opportunity, you must have experience including Involvement in or use of large-scale WES/WGS data sets such as GO-ESP, 1,000 Genomes Project, CHARGE consortium, Centers forMendelian Genomics, ExAC, etc; Experience with multiple platforms (chip-based genotyping, WES & WGS, Sanger, custom capture targeted sequencing, etc) as well as additional genomic profiling technologies (microarrays, RNASeq, etc); Experience with molecular characterization and functional studies geared towards elucidating gene functions and the mechanistic basis for genetic associations, Familiarity with clinical genetics and various genetic models of disease. and a PHD with 5+ years experience in human genetics research and a translational genetics focus.

The following experience would be an added asset, including experience with genetic analyses involving complex loci (e.g. HLA, 17q21.31) and relevant methods and tools; and experience in neurogenetics studies.

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.