Senior Associate Scientist, Delivery Sciences

Cambridge, MA, United States
Nov 23, 2020
Required Education
Masters Degree/MBA
Position Type
Full time
Our mission:

Developing curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

At Intellia, we are committed to solving the complex challenges of making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to create novel engineered cell therapies for immuno-oncological and autoimmune diseases.

Intellia is seeking a highly skilled and motivated Senior Associate Scientist to join our team. The primary responsibilities for this position will be to routinely prepare nanoparticle-based formulations at varying scales and characterize formulations using advanced analytical methods. Work closely with the scientists on lipid nanoparticle (LNP) design and analytical method development and perform analyses for LNP samples and drug products. Optimize existing analytical methods and formulation processes and generate standard operating procedures (SOPs) and test method documents. Conduct experiments, independently and in collaboration with colleagues in support of project goals. Design, plan and establish experimental workflows. Acquire and analyze respective data to inform decision making. Trouble-shoot experiments and instrumentation to reach desired goals. Communicate research and development findings with internal and external partners. Operate and maintain multiple laboratory instruments. Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering and receiving of lab supplies.

    • Support formulation efforts including optimization and characterization
    • Provide high quality, well characterized nanoparticles for in vitro and in vivo evaluation
    • Conduct experiments, independently and in collaboration with colleagues to support projects
    • Design, implement, troubleshoot and modify experiments to reach desired goals
    • Communicate research and development findings with internal and external partners
    • Operate and maintain multiple laboratory instruments
    • Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering and receiving of lab supplies
    • Design, prepare and characterize nanoparticle-based formulations for delivery of nucleic acids

    • Requires a master's degree in Pharmaceutical Sciences, Chemical Engineering, Analytical chemistry or a directly related field plus five (5) years of biotech or pharmaceutical experience.
    • Experience with novel delivery systems including lipid nanoparticles and their analytical characterization
    • Extensive experience with UPLC/HPLC-based analytics and experience developing and running routine assays and novel assay development
    • Able to develop and implement SOPs for novel analytical methods
    • Experience with preparation of nanoparticle-based formulations at different scales sufficient to support in vitro and in vivo studies (rodents).
    • Experience in characterizing and developing novel drug delivery systems for nucleic acids, proteins or small molecules

    • Attention to detail
    • Exceptional time management
    • Effective communication skills (both written and oral)
    • Ability to work independently and collaboratively


What Intellia Stands For:

We push boundaries. We are focused on positively disrupting health care treatment of patients with genomic diseases. The values we live by and drivers we look for are:

- One is respect for individuals; our unique qualities and strengths; our own ways to understand, learn and improve. One is our single-minded determination to excel; to succeed together. One is you and us - trusting and counting on every single one of us.

- Explore because we seek new ways to tackle disease. Explore with unbounded from assumptions, open to ideas. Explore by staying curious, by pushing boundaries, overcoming obstacles. Explore means thinking of new ways.

- Disrupt by thinking courageously...and creating a better future. Disrupt by defying conformity; interrogating the status quo; questioning our momentum. Disrupt with challenging thoughts...with that breed of skepticism that shows you have better solutions.

- Deliver with your focus on the objective and your determination to complete the task. Deliver by advancing relentlessly and by maintaining high standards...even when nobody is watching. Deliver by staying accountable and pulling your weight. Deliver because patients are counting on us to make the promise reality. Get it done.

POSITION: Full-Time, Exempt

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Intellia's web-based application process is managed through Lever. Information submitted through application forms is collected by Lever and subject to Lever's privacy policy .