NGS Senior Scientist - Biologics Optimization

Thousand Oaks, CA, US
Nov 20, 2020
Required Education
Bachelors Degree
Position Type
Full time
The Biologics Optimization team is seeking an experienced Senior Scientist with expertise in NGS to join our team in Thousand Oaks. Biologics Optimization is a multidisciplinary team in Research with capabilities in protein engineering, cloning, expression, purification, and analysis of therapeutic proteins. The group is responsible for the engineering, production, assessment, and final selection of large molecule drug candidates that advance to Process Development.

The Senior Scientist will manage the NGS laboratory and staff, and will be responsible for execution of multiple complex NGS workflows supporting diverse partner teams. The Senior Scientist will be presented with a variety of scientific challenges, and a strong candidate will have a track record of developing and productively implementing cutting edge technologies including informatics and assays.

Position Responsibilities

Manage daily activities of NGS laboratory staff with responsibility for end-to-end delivery of NGS sequencing for multiple customer groups within Amgen Therapeutic Discovery

Work independently to optimize NGS workflows, including both wet lab and informatics, and keep current with the state of the art in sequencing technologies

Innovate and implement additional assays to support biologic drug discovery in collaboration with partner groups in Therapeutic Discovery

Build strong collaborative relationships within the company

Required Skills

NGS experience across Illumina and other sequencing platforms and preparation kits

Experience in management of laboratory staff and in independently tracking and accomplishing functional group deliverables, including excellent organizational skills

Basic experience with informatics and NGS data analysis

Proven success optimizing assays and workflows in an industrial biopharma or other setting

Preferred Skills

Advanced informatics or data science skills including computer programming, e.g., in Python or C++

Deep understanding of molecular biology, especially as applied to recombinant protein production

Experience with biophysical assays on recombinant proteins including binding assays

A track record of innovation as evidenced by patents and/or peer reviewed publications

Basic Qualifications

Doctorate degree with 2 years of scientific experience


Master's degree and 5 years of scientific experience


Bachelor's degree and 7 years of scientific experience

Preferred Qualifications

PhD in life sciences, chemical/biochemical engineering, or a related discipline

4 or more years of relevant post-graduate work experience in an industrial environment

At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our "people-first" philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business.

Consistent with our core leadership value of "Develops the Best Team," we are seeking leaders that prioritize the development of talent. As a manager, your first priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development. Ways that you will display your leadership acumen in this role include:
  • Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams
  • Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities
  • Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business
  • Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement
  • Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages
  • Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.