Senior Research Associate - In Vivo Pharmacology

Who You Are

This is an exciting opportunity for a highly motivated Research Associate- Senior Research Associate to contribute to drug discovery activities for the development of novel small molecule cancer therapeutics as part of our cancer biology discovery team.

The successful candidate will collaborate with team members to conduct a variety of in vitro and in vivo oncology research techniques including biochemistry, molecular, cellular biology, and rodent oncology models.

This position also requires some lab management and operational tasks. We are looking for a talented and enthusiastic individual, who thrives in a collaborative, fast-paced, and growing environment to join our team.

Responsibilities

• Execution of in vivo (tumor implantation and dosing) and ex-vivo pharmacology experiments (target and mechanism engagement) to assess the inhibition or activation of novel targets in the oncology setting
• Assist in the planning and design of experiments using mostly (but not limited to) small molecule therapeutics
• Assist in ex vivo tissue processing and in vivo rodent model development and use
• Interpret and communicate experimental data in collaboration with supervisor
• Record keeping in written and electronic laboratory notebooks
• Lab Inventory, equipment and functionality management

Education, Experience & Skills Requirements

• A highly motivated, committed individual with good organizational skills
• BS/MS in a biology-related discipline
• BS and 4 years, or MS and 1-year hands-on experience in a cell/molecular biology laboratory (Oncology setting highly preferred)
• Experience with oncology in vivo models: xenografts and syngeneic, tumor measurements, ex-vivo pharmacodynamics
• Experience with mammalian cell culture, protein expression quantification (ELISA, MSD, FACS), RT-PCR, and western blot/immunoprecipitation
• Industry experience preferred
• Strong written and oral communication skills

What We Offer

• Patient Days, where we are fortunate enough to learn more about the lives we are looking to impact and a real exchange of ideas as to how we can improve our efforts
• A culture inspired by our values: put patients first; think independently, be radically transparent; every minute counts, and let the science speak
• Learning and development training to help employees be the best version of themselves
• Collaborative business environment
• Excellent compensation package (Base, Performance Bonus, Stock, RSU programs)
• Excellent benefits package
• Flexible PTO
• With office locations in San Francisco, Boston, New York, and Raleigh, there are ample cross-collaboration opportunities with other BridgeBio Pharma programs
• A fast-paced, data-driven, work environment with world-class R&D minds and capabilities
• Work with the most productive groups of R&D operators in the industry
• Partnerships with leading institutions
• A platform for meaningful scientific contributions to shine
• Commitment to Diversity & Inclusion - with initiatives like Women at Bridge, we are committed to fostering an inclusive environment where every person feels respected for who they are, empowered to contribute, inspired to lead, and supported in their efforts to do so