Senior Scientist - Clinical Cytometry

South San Francisco, CA, US
Nov 17, 2020
Required Education
Bachelors Degree
Position Type
Full time
Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is developing our Translational Science focus with modern molecular and cellular science and pathology laboratories, designed to discover and develop valuable biomarkers in support of our clinical programs.

The Department of Clinical Biomarkers & Diagnostics at Amgen in South San Francisco (ASF) is seeking a highly motivated Senior Scientist to support our efforts to implement flow cytometry based clinical biomarker assays.

The candidate will be an integral member of a dynamic group of science scientific and platform experts. The candidate will collaborate across Amgen's scientific community, interfacing with multiple therapeutic areas across all stages of the commercialization pipeline. The Senior Scientist will bring an in-depth technical knowledge of flow cytometry, in order to drive the development, validation, and implementation of flow cytometry-based assays to support various clinical programs. Specific responsibilities associated with the job include independent critical thinking, choosing the appropriate platform, planning and reviewing assay development and validation activities, analyzing and interpreting data, presenting results to the stakeholders and working effectively with internal and external partners. While this role may require some bench work and technical troubleshooting, this is not primarily a bench-based position.

Basic Qualifications

Doctorate degree and 2 years of relevant scientific experience


Master's degree and 5 years of relevant scientific experience


Bachelor's degree and 7 years of relevant scientific experience

Preferred Qualifications
  • Master's degree with 5+ years of experience in flow cytometry biomarker assay development and qualification
  • Previous experience working in a matrixed environment to execute flow cytometry assay development and validation to support clinical trials
  • Project management skills to meet critical timelines associated with various activities necessary to support biomarker assessment of clinical samples using flow cytometry
  • Deeper understanding of processes involved in clinical sample management
  • A strong background in multiparametric flow cytometry assays including immunophenotyping and immune based functional assays
  • Knowledge of instrumentation including traditional flow cytometry, spectral flow cytometry and mass cytometry
  • Well versed in complex flow cytometry data analysis using DIVA, FlowJo, FCS Express, SPADE, viSNE and CITRUS
  • Demonstrated track record of critical independent thinking and troubleshooting ability
  • Ability to multi-task and manage multiple studies, strong verbal and written communication skills with a high degree of motivation, creativity and collaborative qualities
  • Must be able to work and coordinate with internal stakeholders as well as external partners such as CROs and vendors to support outsourced activities
  • Familiarity with processes and factors needed to evaluate, qualify and manage CROs

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.