Research Scientist, Bioinformatics

Employer
Kite Pharma
Location
Santa Monica, CA, United States
Posted
Nov 15, 2020
Ref
R0016115
Required Education
Doctorate/PHD/MD
Position Type
Full time
Kite is continuing to hire for all open roles. Our interview process may be conducted virtually and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensure the health and safety of our teams.

For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job

Job Description

At Kite Pharma we are revolutionizing the treatment for cancers through immunotherapy through novel breakthrough technology. We have developed and launched best in class CAR-T therapy Yescarta, currently curing patients of previously intractable b-cell malignancies. We are using our expertise to apply our success to other indications, and you can help!

We are seeking a Research Scientist with a deep understanding of the current experimental methodologies used in the biological space, including high-throughput genomics and proteomics technologies as well as predictive modeling with experience in statistical analysis and bioinformatics algorithms.

The successful candidate will have demonstrated the ability to synthesize scientific questions into a coherent research effort and communicate scientific findings across the different research functions.

We offer a cutting edge benefit package focusing on work/life balance, affordable options, matching 401k, relocation, etc.

Responsibilities include, but are not limited to:
  • Lead the establishment, analysis, and interpretation of DNA and RNA NGS sequencing data and build analytical workflows for automated deployment of bioinformatics tools in the cloud and high-performance computing environments, including SaaS bioinformatics providers like Seven Bridges, for interpreting NGS data.
  • Analyze and interpret large molecular data sets, including mining of immunological datasets for e.g. biomarkers, therapeutic targets, cancer mutations.
  • Serve as a liaison in technology and knowledge transfer efforts in bioinformatics solutions from external partners in academia and industry.
  • Contribute to company-wide scale-out of bioinformatics infrastructure and solutions as well as external scientific discussions on technology evaluation.
  • Work closely with research and cross-functional teams to jointly advance the development and improvement of manufacturing processes, designing fit T Cells and enhancements to CAR T-Cells programs.
  • Analyze and interpret molecular large data sets, including mining of immunological datasets e.g. biomarkers, therapeutic targets, cancer mutations.
  • Coordinate deliverables jointly with clinicians, molecular biologists, IT, commercial and other departments.


Basic Qualifications:
  • Ph.D. degree in Bioinformatics, Computational Biology or a closely related field with 5+ years of post-doctoral academic or industry experience.


Preferred Qualifications:
  • Full proficiency in R and/or Python, experience in Linux environments and cloud computing systems, and the development of statistical methods and algorithms is required.
  • Proficiency in building and maintaining large scale bioinformatics analysis pipelines for NGS data, and statistical programming languages.
  • Hands-on experience with the bioinformatics analysis of single-cell, flow cytometry, mass spectrometry, and mass cytometry data analysis is required.
  • Evidence of a successful academic or industry track-record
  • Hands-on experience applying computational tools to study cancer mutations and T cell immunity, in particular, experience in Illumina sequencing data and NGS pipelines, analysis of cancer genomic datasets is required.
  • Experience with remote data storage and management (e.g. Amazon Web Services) is required
  • Strong understanding of statistics and the ability to generate robust statistical models for predicting outcomes in multidimensional data.


Does this sound like you? If so, apply today!

*LI-SB1

IND-123

Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com. Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma.

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For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.