R&D Associate - Drug Product Process Development

Tarrytown, NY, United States
Nov 15, 2020
Required Education
Bachelors Degree
Position Type
Full time
Regeneron's Formulation Development Group (FDG) is seeking an R&D Associate who will support planning, optimization, and execution of Drug Product process-based unit operations and assist in developing scale-down models. Our new Associate will work closely with FDG leads/scientists, support development activities across multiple programs, and ensure a seamless technology transfer to the manufacturing team. This Associate will also support full functionality and maintenance of the state-of-the-art process development facility, including procurement, installation, and operation of tools and equipment. Additionally, you will independently design, execute process development and analytical characterization studies, and document the same in electronic lab notebook.

A Typical Day In The Role Might Look Like:
  • Manage equipment installation, operation, maintenance, calibration, and repairs.
  • Work closely with key members of formulation development and facility management teams to ensure full functionality of Drug Product Pilot Facility (DPPF).
  • Procure consumables and continuously update the inventory for the DPPF.
  • Independently design and execute Drug Product (DP) process development activities for different unit operations across multiple programs.
  • Assist in developing small scale models to effectively mimic manufacturing unit operations and support technology transfer to manufacturing teams.
  • Work very closely with FDG leads/scientists to ensure seamless progression of multiple late-stage process-related activities.
  • Able to effectively engage with others and work in cross-functional teams to support process development.
  • Communicate relevant information in a clear and transparent manner, and effectively collect information through strong listening skills.
  • Bring in new ideas from literature or external practices, and engage in active questioning to understand context and interpretation of work.
  • Demonstrate strong problem-solving skills.
  • Prepare, review, and edit technical reports.
  • Comfortably shift gears and priorities to meet changing business needs as required.

This Job Might Be For You If:

  • You have strong initiative and drive to complete challenging tasks and learn new technologies.
  • You are capable of multi-tasking, working both independently and within a team environment.
This position requires a BS degree in Biomedical or Chemical Engineering, Pharmaceutical Sciences, or related field with at least 1 - 3 years of relevant industry experience. Experience with Drug Product (formulation and process) development and characterization. Solid understanding of analytical instruments used for protein therapeutics characterization, such as HPLC-based chromatographic techniques (icIEF, SEC, IEX), biophysical methods (DLS, DSC, and UV-Vis), and particle characterization methods (MFI and HIAC). Prior research experience in the areas of protein structure, stability, and protein aggregation. Basic understanding of common protein degradation pathways. Ability to work independently or in a team setting; strong problem-solving skills; quickly adapt to change to support accelerated timelines; efficient time management. Experience with coding and statistical software is a plus (JMP, R).

Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides amazing benefits including health and wellness programs, fitness centers and stock for employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or maternity status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.