Senior Principle Research Scientist

Lake County, IL, United States
Nov 14, 2020
Required Education
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

*This position can sit out of the Bay Area*

AbbVie Precision Medicine is seeking a highly motivated and experienced translational scientist to advance our oncology late-stage clinical pipeline and approved medicines through translational research. The scientist will work in a fast-paced and a multi-disciplinary team on data analysis and experimental execution of different aspects of translational research strategy. He / she will function as a principal investigator, lead a team of scientists to generate original research and interrogating new hypotheses to advance AbbVie's assets through external and internal efforts, informing clinical development strategies.

Key Responsibilities:
  • Define and implement translational research strategies for multiple oncology therapeutic programs. Interrogate disease/target biology, implement and interpret data from preclinical and clinical studies to conceive and execute novel scientific research internally or externally to support advancement of AbbVie's oncology late-stage pipeline and approved therapeutics.
  • Design experimental strategies to elucidate sensitivity and resistance mechanisms to the therapeutics and identify/validate mechanism-based combinations to guide the clinical team on indication expansion and combination options.
  • Initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a clinical development program
  • Lead a team of highly experienced and accomplished scientists and develop productive collaborations with cross functional teams.
  • Foster external collaborations. Develop productive collaborations and communications with external subject matter experts. Prioritize and manage multiple external collaborative research activities/proposals. Maintain a broad range of scientific knowledge and technical expertise in cancer biology.
  • Strong communication and teamwork skills are essential as the candidate is expected to interact with diverse groups within AbbVie and external collaborations.
  • Prepare and present summaries of translational data to key stakeholders across multiple functional areas, including Drug Discovery, Development, Precision Medicine, Regulatory, Commercial, and others.


Basic Qualifications:
  • PhD; MS; BS in Cancer Biology, Cell Biology, Molecular Biology, Immunology or related field with 10+ years (PhD); 16+ years (MS); or 18+ years (BS).
  • Proven track record of accomplishments in the cancer field.
  • Excellent interpersonal and written/verbal communication skills are must.
  • Demonstrated ability to work successfully in a team environment.
  • Demonstrated critical thinking skills as well as excellence and productivity in independent research.
  • Must be proactive and able to work effectively on multiple projects in a fast-paced, dynamic environment.

Preferred Qualifications:
  • M.D. and/or Ph.D. in Cancer Biology, Cell Biology, Molecular Biology, Immunology or related field with at least 10+ years of relevant postdoctoral cancer research experience in academia or pharma industry.
  • Strong background and expertise in apoptosis and/or hematological malignancies and/or classical oncogenic signaling pathways is strongly preferred.
  • Demonstrated excellence and productivity in independent research. Experienced and demonstrated success as primary author of publications, presentations and/or primary inventor of patents.
  • Demonstrated ability to function as a principle investigator, generating original ideas and research or development strategies.
  • Demonstrate creative 'out of the box' thinking to solve difficult problems.

Key Leadership Competencies
  • Builds strong relationships with peers and cross functionally with partners to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality.
  • Strong interpersonal and communication skills with demonstrated ability to work within a team environment.

Significant Work Activities
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Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.