Senior Associate Scientist, Upstream

Austin, TX, USA
Nov 14, 2020
Required Education
Bachelors Degree
Position Type
Full time
Company Description:

Molecular Templates (MTEM) is a clinical stage biopharmaceutical company targeting a variety of cancers through development of its innovative proprietary Engineered Toxin Body (ETB) platform. MTEM's first immunotoxin, MT-3724, is in clinical development for non-Hodgkin's lymphoma. Pipeline products for additional oncology targets are being advanced toward clinical development. For more information, please visit MTEM's website at

Position Overview:

Molecular Templates is seeking an experienced and highly motivated professional to support upstream processing for production activities. This Exempt position will perform functions related to production and GMP manufacturing operations, including routine protein expression using microbial fermentation, equipment set-up and calibration, and media preparation. This position will also be responsible for general facility and equipment preventative maintenance and sanitization. This will require excellent technical skills and strict adherence to Standard Operating Procedure (SOP) guidelines and verbal instructions and accurate and timely completion of manufacturing batch records.

Job Responsibilities will include:
  • Perform protein expression by microbial fermentation. This includes but not limited to: cell culture, cell banking, bioreactor operation, cell plating, cell harvesting, media preparation, equipment cleaning and sterilization, process data recording.
  • Work on problems of moderate scope where analysis of situations or data requires a review of a variety of factors.
  • Exercise judgment within defined procedures and practices to determine appropriate action. Builds productive inter- and intra-group working relationships.
  • Complete required documentation in an accurate and timely manner, strictly adhering to established SOPs and regulatory requirements.
  • Adhere to production schedules and timelines
  • Ensure highest degree of personal safety and facility security throughout operations
  • Conduct general laboratory and equipment maintenance duties, including washing glassware, ordering raw materials, products and other resources, and maintaining inventory (e.g. buffer), conducting preventative and safety checks on facility and equipment

  • Bachelor's Degree + 5 years relevant experience in GMP manufacturing environment or laboratory conducting or supporting protein expression methods using microbial fermentation, or Master's Degree + 2 years, or a Ph.D. in a relevant field of study + no additional experience
  • Experience in biopharmaceutical industry preferred
  • Demonstrated experience and comprehensive knowledge of upstream processing activities required
  • Excellent written and verbal communication skills
  • Proficient computer skills with knowledge of spreadsheet and word processing
  • Excellent problem-solving and analytical skills
  • Excellent organizational, time management and multi-tasking skills
  • Ability to meet deadlines and maintain production schedule
  • Ability to follow written and verbal instruction and work under supervision
  • Ability to understand and exercise basic mathematical calculations
  • Ability to work in a fast-paced, high-growth team environment
  • Ability to lift 75 lbs. manually or with additional assistance from staff and/or mechanical lifting equipment (e.g. dolly, cart, lift, hand truck, etc.). Must be able to stand, crouch, sit, bend, or stretch for extended periods of time.
  • Must possess flexibility to work varying schedules to support operations, such as occasional 12-hour shift, night shift and possible weekend or holiday work

Reporting Structure:

This position has no supervisory responsibilities. This position reports to the Manager, Upstream Process Development.

Molecular Templates, Inc. is an Equal Opportunity Employer and offers competitive salaries and benefits.

Molecular Templates Inc