Associate Scientist, Delivery Science (Formulation / Analytical Development)

Location
Cambridge, MA, United States
Posted
Nov 13, 2020
Ref
454023926
Hotbed
Genetown
Required Education
Bachelors Degree
Position Type
Full time
Our mission:

Developing curative genome editing treatments that can positively transform the lives of people living with severe and life-threatening diseases.

At Intellia, we are committed to solving the complex challenges of making CRISPR/Cas9-based medicines a reality for patients suffering from genetic diseases and to create novel engineered cell therapies for immuno-oncological and autoimmune diseases.

SUMMARY:

Intellia is seeking a highly skilled and motivated Research Associate to join our team. The primary responsibilities for this position will be to prepare and characterize formulations for the delivery of nucleic acids and proteins for biological applications.

GENERAL RESPONSIBILITIES:
    • Support formulation efforts including optimization and characterization
    • Provide high quality, well characterized material for in vitro and in vivo evaluation
    • Conduct experiments, independently and in collaboration with colleagues to support project goals
    • Design, implement, troubleshoot and modify experiments to reach desired goals
    • Communicate research and development findings with internal and external partners
    • Operate and maintain multiple laboratory instruments
    • Assist in maintaining general laboratory functionality, including lab equipment maintenance and the ordering and receiving of lab supplies


SKILLS:
    • Design, prepare and characterize formulations for the delivery of nucleic acids and proteins
    • Collaborate with internal groups in pharmacology and biology to support in PD/PK/Tox studies.
    • Preferably has experience with lipid-based nanoparticle formulations.
    • Preferably has experience with analytical techniques relevant for characterizing nanoparticle formulations (i.e. particle size, fluorescent assays, HPLC/UPLC, etc).
    • Preferably has experience with Tangential Flow Filtration (TFF)


QUALIFICATIONS:
    • Bachelor's Degree with 2-5 years of industry experience or M.S. (in Engineering, Chemistry, Materials or Pharmaceutical Sciences).
    • Experience with production of nanoparticle formulations at scales sufficient for in vivo work a plus. A strong background in physics/soft matter/bio-membranes is desired but not required.


#LI-DG1

What Intellia Stands For:

We push boundaries. We are focused on positively disrupting health care treatment of patients with genomic diseases. The values we live by and drivers we look for are:

- One is respect for individuals; our unique qualities and strengths; our own ways to understand, learn and improve. One is our single-minded determination to excel; to succeed together. One is you and us - trusting and counting on every single one of us.

- Explore because we seek new ways to tackle disease. Explore with unbounded minds...free from assumptions, open to ideas. Explore by staying curious, by pushing boundaries, overcoming obstacles. Explore means thinking of new ways.

- Disrupt by thinking courageously...and creating a better future. Disrupt by defying conformity; interrogating the status quo; questioning our momentum. Disrupt with challenging thoughts...with that breed of skepticism that shows you have better solutions.

- Deliver with your focus on the objective and your determination to complete the task. Deliver by advancing relentlessly and by maintaining high standards...even when nobody is watching. Deliver by staying accountable and pulling your weight. Deliver because patients are counting on us to make the promise reality. Get it done.

POSITION: Full-Time, Exempt

EEOC Statement: Intellia believes in a diverse environment, and is committed to equal employment opportunity for all its employees and qualified applicants. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Intellia will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Intellia's web-based application process is managed through Lever. Information submitted through application forms is collected by Lever and subject to Lever's privacy policy .