Cell Biologist/Immunologist

Location
Pasadena, CA, United States
Posted
Nov 10, 2020
Ref
4204194003
Discipline
Science/R&D, Biology
Hotbed
Biotech Beach
Required Education
Doctorate/PHD/MD
Position Type
Full time
Company Overview: Terray Therapeutics is a venture backed biotechnology company utilizing a novel spatially encoded screening and optimization platform to develop treatments for historically intractable causes of human disease. The Company's platform technology provides comprehensive, quantitative affinity binding data at a completely unprecedented scale. Our internal development programs are focused on oncology and immunology. In addition to these programs we also work with leading pharmaceutical companies. Our platform is based on fluorescent imaging of ultra-dense microarrays such that, via thousands to millions of images, we can measure billions of target/molecule interactions in a day, generating hundreds of millions of dose-response binding curves.

Position Summary: Terray Therapeutics is seeking a motivated, creative, and experienced cell biologist/immunologist to join our biology team. The candidate will play a key role in designing and optimizing a wide-range of biochemical and cell-based assays and implementing these to evaluate hits from screens and drive lead optimization. The position will report to the Head of Biology.

The core responsibilities of this job will be
1. Design and optimize biochemical and cell-based assays specific to therapeutic targets of interest
2. Adapt assays for medium to high-throughput screening of small molecule hits from our affinity screens
3. Design and execute studies to fully characterize the mechanism of action of small molecules
4. Analyze data and communicate results
5. Help evaluate and set up new lab instrumentation
6. Support organization of lab and equipment as needed

Experience and Qualifications: Given the company's size, anticipated growth and fast-paced environment, the organization requires a Scientist who is thoughtful, high energy and can partner with the broader organization to further enhance our next generation drug discovery capabilities.

Part of Terray Therapeutics' success is nurtured by a hands-on work environment where everyone is accountable, everyone is vested in a vision of excellence, and everyone actively takes part in the success of the business. Terray Therapeutics supports a positive work environment comprised of engaged employees who feel appreciated, recognized and free to be creative.

Qualifications include:
• PhD with 2-5 years of research experience in the field of immunology, oncology, cell signaling pathways, molecular biology or biochemistry
• Background in small molecule drug discovery preferred
• Extensive hands-on experience with cell culture and cell-based assays including reporter assays, and proliferation/viability/apoptosis assays as well as cytokine and gene expression analysis
• Proficiency in primary cell isolation, differentiation and culture and flow cytometry preferred
• Experience with small molecule mechanism of action studies desired
• Experience with biochemical assays and molecular biology techniques a plus, particularly immunological assays
• Excellent organizational, interpersonal and communication skills and can thrive in a highly collaborative research environment
• Demonstrated technical proficiency, ability to troubleshoot to solve problems and to deliver high quality data

She/he will exhibit the ability to work well under pressure to provide results in a short timeframe. The company is looking for a highly responsive, goal-oriented individual who will bring significant energy and drive to solve complex technical problems and help us achieve our mission to advance human health.