Senior Scientist - Medicinal Chemistry

Thousand Oaks, CA, US
Nov 07, 2020
Required Education
Associate Degree
Position Type
Full time
Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in Thousand Oaks, CA (ATO).

This Senior Scientist role will be part of an innovative Medicinal Chemistry group with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development, including opportunity to work within Amgen's Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. The Senior Scientist may directly or indirectly manage research scientists and/or associates within a collaborative environment and be responsible for providing motivating professional development coaching within his/her group. Additional responsibilities include but are not limited to: devising and implementing creative scientific strategies to address synthetic and medicinal chemistry issues through conducting laboratory experiments, working closely with other researchers to influence team direction and advance programs, communicating progress and strategy in various forums, and preparing technical documents. The Senior Scientist will serve as a scientific resource to the department who will champion new technologies/ideas to enhance capabilities.

Basic Qualifications
  • Doctorate degree and 2 years of medicinal chemistry or pharmaceutical research experience
  • OR
  • Master's degree and 5 years of medicinal chemistry or pharmaceutical research experience
  • OR
  • Bachelor's degree and 7 years of medicinal chemistry or pharmaceutical research experience

Preferred Qualifications
  • Doctorate degree in chemistry specializing in organic synthesis
  • 6+ years of experience in synthetic organic or medicinal chemistry
  • Experience leading/participating on a team that has advanced compounds to clinical development
  • Track record of consistent and successful drug discovery accomplishments (e.g., patent inventorship, conference presentations, and peer-reviewed publications)
  • Deep understanding of synthetic and medicinal and chemistry concepts with high lab productivity
  • Demonstration of good lab practices, with particular attention to safety
  • Proficient skills in parallel synthesis and use of structure-based or other computer-aided design tools
  • Broad understanding of drug discovery disciplines (e.g., chemistry, biology, safety, PKDM, etc.)
  • Experience managing direct reports or coaching others (internal or CRO)
  • Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live cell-therapies.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.