Global Head Neuroscience Computational Biology

Cambridge, MA, United States
Nov 04, 2020
Required Education
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

AbbVie is seeking a creative and experienced leader of our Neuroscience Computational Biology team to use quantitative analyses and data integration from discovery sciences to the clinic for accelerating efforts to develop innovate therapeutic approaches for neurodegenerative diseases. The successful candidate will be responsible for bioinformatic strategy to deliver and validate novel targets as well as to identify novel biomarkers. To be successful, you will need deep and broad computational science expertise along with accomplished communication and influencing skills. You will be able to balance strong creativity and enthusiasm with an ability to focus and create tangible and impactful results.

The successful candidate will be the leader of Neuroscience Computational Biology, which consists of three teams located at Neuroscience sites: Cambridge (MA), Ludwigshafen (Germany) and North Chicago (IL). The position is centered in Cambridge and the successful candidate will develop the vision and strategy to lead the cross-functional interface of Neuroscience Discovery groups, Development, Genomic Research Center (GRC) and other organizations (internal and external).

AbbVie's Neuroscience R&D seeks novel therapeutic approaches that will have a remarkable impact on patients with neurodegenerative diseases. The focus areas are Alzheimer's and Parkinson's disease, but includes other adjacent disorders such as multiple sclerosis and stroke.

AbbVie's GRC is a center of excellence for bioinformatics, functional genomics, human genetics, pharmacogenomics and has access to various population cohorts (over 1 million genomes). The GRC works across all R&D, and multiple areas such as process sciences and corporate strategy. Additionally, AbbVie is expanding its data strategy portfolio to advance Precision Medicine.

The key responsibilities:
  • Set the global strategy for Neuroscience Computational Biology for target identification and biomarker research in close alignment with AbbVie's Neuroscience objectives.
  • Shape innovative approaches to drive the Neuroscience portfolio forward and bridge across all R&D, including but not limited to integration of OMICS data especially single cell level technologies, translational biomarker research, genomics cohort information, and clinical trials.
  • Drive bioinformatics methods development, implementation and benchmarking and contribute to bioinformatics pipeline and tool development.
  • Identify and implement key collaborations with external partners.
  • Serve as key person and guardian for ensuring close communication and collaboration between Computational Biology and wet lab research within Neuroscience Discovery, Development and other key stakeholders and relevant organizations.
  • Lead, motivate, inspire and develop diverse, cross-functional teams in a highly matrixed, multi-cultural global environment.
  • Maintain a 'one Computational Biology' spirit within Neuroscience and participate in the global Computational Biology organization led by the GRC.
    This leader will grow their program in headcount and influence



  • Doctoral degree or PhD in Bioinformatics, (Bio)Statistics, (Bio)Mathematics, Genetic Epidemiology or Biology/Medicines/Genomics related disciplines with a strong focus on data analysis. An MD would be advantageous for helping to shape our Development Computational Biology programs.
  • A minimum of 10-years experience in Computational Biology in pharmaceutical or biotechnology research and drug development in Neuroscience. A minimum of 5 years in Alzheimer's and/or Parkinson's Disease research or other neurodegenerative diseases.
  • Strong and up-to-date hands on and deep knowledge of data analysis and/or data sciences.
  • Excellent scientific and managerial track record. Experience in leading external collaborations.
  • Experience in leading multidisciplinary teams and working in a cross-functional international environment.
  • Ability to travel up to 20%

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Yes, 20 % of the Time
Job Type
Job Level Code
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.