Executive Director, Biologics Optimization

Thousand Oaks, CA, US
Oct 31, 2020
Required Education
Bachelors Degree
Position Type
Full time
Executive Director, Biologics Optimization

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

We are looking for a highly motivated, hardworking individual to lead our Biologics Optimization function. Our laboratories convert prioritized antibody repertoires (and additional novel proteins) into lead biologic therapeutics, with affinities, activities, cross-species specificities, valencies and manufacturability. The laboratory also works closely with Process Development colleagues to develop and evaluate protein scaffolds and architectures for the improvement of Amgen's innovative biologics platform. The candidate will have the opportunity to contribute directly to the discovery of potential medicines through sophisticated cellular and protein engineering on a wide variety of therapeutic targets derived from human genetics and biological insight.

Reporting into the Vice President of Biologics, the Executive Director, Biologics Optimization will be responsible for multiple laboratories engaged in biotherapeutics discovery using a wide range of ground breaking modeling, cell biology and bioprocess techniques with key responsibilities for scientific outreach and engagement with academic, governmental and non-profit biologics laboratories. Responsibilities will include:
  • Making operational decisions to perfect protein targets for development into therapies
  • Co-creating with Process Development the strategies that will further advance Amgen's leading position in multi-specific biologics, novel engineered proteins, and live-cell therapies
  • Leading and developing a team of 50 scientists that deliver critical elements of Amgen's pipeline
  • Representing Amgen's protein engineering and cellular expression research capabilities to the academic community
Basic Qualifications:
  • PhD and/or MD and 6 years of experience in Protein Chemistry and Engineering OR
  • Master's degree and 10 years of experience in Protein Chemistry and Engineering OR
  • Bachelor's degree and 12 years of experience in Protein Chemistry and Engineering AND
  • 6 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources
Preferred Qualifications:
  • PhD in protein biochemistry, structural biology, bioprocess engineering or a related field
  • 15+ years of industry experience in biotherapeutics discovery
  • Knowledge of state-of-the-art protein engineering, bioprocess and modeling technologies
  • Extensive knowledge and practical experience in cellular and protein engineering, and the delivery of clinically meaningful therapies
  • Ability to lead a large and highly sophisticated industrialized scientific laboratory
  • Demonstrated high-level institutional leadership skills and impact that may include membership of advisory or governing boards of academic appointments, governmental funding oversight, scientific journal editor, Directorship of research facilities or institutes, Directorship of biopharmaceutical laboratories
  • Excellent presentation (written and oral) and social skills applicable to a wide variety of constituencies

Amgen's Commitment to Our Staff

At Amgen, our mission is serving patients. Our staff are dedicated to pushing the boundaries of science to transform medicine and turn the tide on serious illnesses. Central to achieving this mission is our "people-first" philosophy. We recruit the best talent, build an environment that facilitates career growth, and provide staff with the opportunity to make significant contributions for patients and our business.

Consistent with our core leadership value of "Develops the Best Team," we are seeking leaders that prioritize the development of talent. As a manager, your priority and primary role is to accelerate the performance and development of your team. We expect managers to exemplify strong leadership and champion self-awareness and career development Ways that you will display your leadership acumen in this role include:
  • Mentoring, coaching, and developing staff to build highly-skilled, diverse, and inclusive teams
  • Fostering a positive and respectful work environment that encourages staff retention and motivates individuals to work toward common goals and priorities
  • Ensuring that staff understand how their efforts and contributions make a meaningful impact to the business
  • Growing core skills and capabilities among staff, particularly in learning agility, problem solving, strategic and creative thinking, flexibility, resilience, effective communication, prioritization, delivery of results, and continuous improvement
  • Making accurate evaluations of your team's skills and competencies and providing timely and respectful feedback, including direct delivery of difficult messages
  • Developing an understanding of your team's career objectives and serve as a thought-partner in their career development plans
  • Assisting staff with preparing for roles of growing responsibility and identifying new opportunities that expand their skills and align with their overall career objectives
  • Resolving critical gaps in the organization's internal capabilities and skillsets, including strategic external recruiting
  • Identifying diverse, qualified successors for key positions
  • Ensuring that direct reports who also lead people consistently demonstrate these same behaviors with their staff

We understand that to successfully sustain and grow as a global enterprise and deliver for patients - we must ensure a diverse and inclusive work environment.

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

MEANINGFUL IMPACT. To serve patients. We are all deeply committed to our mission: to serve patients. And we all have opportunities to contribute to that mission in meaningful ways. This creates a powerful sense of shared purpose.

INNOVATIVE: Stretch yourself at the cutting edge. You're poised to have a high impact in the new Bio century, Amgen offers our people interesting and challenging work.

REPUTATION. Be behind world-renowned products and services. With our industry reputation and strong product pipeline, you can take pride in working at Amgen.

COLLABORATIVE. Work alongside the best. Be part of our highly talented, hard-working teams. Their spirit is what fuels our success.

REWARDING. Get a fair share in success. Everyone's contribution is recognized - and strong performance is rewarded.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.