Research Associate I, Biology (Protein Sciences)

Location
Brisbane, California, United States
Posted
Oct 31, 2020
Ref
847749576
Hotbed
Biotech Bay
Required Education
Bachelors Degree
Position Type
Full time
SUMMARY:

We are seeking a knowledgeable and self-motivated Research Associate to join our Protein Sciences Group within the company's Research Division. In this laboratory-based position, the successful candidate will work to purify a diverse repertoire of proteins for the company's drug discovery efforts, contributing to compound screening and mechanism characterization pipelines. The candidate should be capable of designing, executing, and troubleshooting experiments independently, bringing enthusiasm and creativity to their work.

ESSENTIAL DUTIES AND RESPONSIBILITIES:
  • Purification of a wide variety of native and recombinant proteins, working with multiple source materials (muscle, yeast, bacteria, etc.)
  • Characterization of protein samples to determine parameters such as purity, activity, and recovery
  • Documentation of experimental data, maintaining well organized laboratory records, and presentation of findings at group or department meetings
  • Ensuring efficient laboratory operations: preparing stock solutions and other reagents, managing lab inventories, maintenance and troubleshooting of equipment
  • Collaborating with other team members and taking initiative to identify problems and improve procedures


EDUCATION/EXPERIENCE/SKILLS:
  • BS in biochemistry, molecular biology or related field. 3-5 years of applicable experience is a plus
  • Proficient with chromatographic purification systems (e.g. AKTA) and affinity, ion-exchange, hydrophobic, and size-exclusion chromatography
  • Experience with batch purification techniques (precipitation, filtration, ultra-centrifugation, etc.) and cell disruption (e. g. microfluidization)
  • Experience with protein characterization techniques such as SDS-PAGE, Western blot, SEC-HPLC, spectroscopy, and enzyme kinetics
  • Excellent laboratory skills. Ability to generate accurate, reproducible, and actionable data.
  • Good interpersonal, communication, and presentation skills