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Senior Associate Scientist - Medicinal Chemistry

Employer
Amgen
Location
Thousand Oaks, CA, US
Start date
Oct 30, 2020

View more

Discipline
Science/R&D, Biotechnology, Chemistry
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Beach, Best Places to Work

Job Details

Amgen is a leading global biotechnology company, with a mission to serve patients around the world. As a science-based, patient-focused organization, we discover and develop innovative therapies to treat serious illnesses. Our medicines have made a dramatic difference in the lives of millions. To underpin our commitment to serve patients, Amgen is hiring in the department of Medicinal Chemistry at our Research and Development facility in Thousand Oaks, CA (ATO).

This Senior Associate Scientist role will be part of an innovative Medicinal Chemistry group with responsibilities including (but not limited to) the design, synthesis, and purification of novel compounds for potential clinical drug development, including opportunity to work within Amgen's Induced Proximity Platform (IPP), which is focused on novel and innovative approaches to modulate intractable targets in diseases using the emerging PROTAC modality. The Senior Associate Scientist will work in teams to develop, implement and perform organic reactions for ongoing Medicinal Chemistry teams, including troubleshooting of synthetic routes and reactions, scouting of new synthetic routes and performing high difficulty synthetic chemistry. Furthermore, he/she will contribute to the design of new compounds and the development of structure-activity relationships. This individual will perform structural determinations using NMR and mass spectral techniques and purify compounds using a variety of techniques. They will be recognized as a lab leader and should demonstrate excellent verbal and written communication skills. Additional responsibilities include maintaining laboratory notebooks, participating in group and project meetings and, as needed, presenting to groups and aiding in the writing of papers and patent applications.

Basic Qualifications
  • Master's degree and 3 years of laboratory experience
  • OR
  • Bachelor's degree and 5 years of laboratory experience


Preferred Qualifications
  • Doctorate degree in chemistry specializing in organic synthesis by Oct 2020 OR 6+ years of focus or specialization in synthetic organic or medicinal chemistry (academic and/or industrial)
  • Track record of accomplishments (e.g., peer-reviewed publications)
  • Demonstrated ability to scout and troubleshoot synthetic routes, and perform high difficulty synthetic chemistry
  • Clear understanding of structural determination using NMR and Mass Spectral techniques as well as knowledge of purification methods
  • Demonstration of good lab practices, with particular attention to safety
  • Excellent communication skills (both written and oral), leadership skills and the ability to work well in teams


Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology and is matched by an unparalleled toolbox of therapeutic modalities ranging from small molecules to peptides to proteins to antibodies to live-cell therapies.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Company

We are all different, yet we have this in common: our mission to serve patients. This sense of shared purpose is key to our becoming one of the world’s leading biotechnology companies. It guides us as we continue to launch new medicines and reach millions of patients worldwide.

We live the mission.

We win together.

We thrive on continual challenge.

Our team of 22,000+ scientists and professionals worldwide bring distinct perspectives and experiences to all we do. We leverage our global talent to achieve together—to research, manufacture and deliver ever-better products and greater depth to our mission.

At Amgen, there is a strong correlation between our high level of diversity and performance. Because addressing issues with a wider range of perspectives and approaches leads to more creative problem-solving. Together, we’re transforming the promise of science and biotechnology into therapies that have the power to restore health.

Connect with us to explore how you can Win, Live, and Thrive at Amgen.

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Company info
Website
Phone
805-447-1000
Location
Corporate Headquarters
One Amgen Center Drive
Thousand Oaks
California
91320-1799
United States

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