Senior Research Associate, In Vivo Research

Location
Cambridge
Posted
Oct 29, 2020
Ref
4828146002
Hotbed
Genetown
Required Education
Associate Degree
Position Type
Full time
JOB PURPOSE

This position will report directly to a Sr. Scientist in the In Vivo Research group within the department of Gene Therapy. The Senior Research Associate (SRA) will have three primary responsibilities: (1) to execute in vivo studies to support gene therapy research programs at Sana, (2) to carry out cell and tissue preparation work related to in vivo studies, and (3) to support needs across the Gene Therapy organization. The position will also require close communication and collaboration with research groups at Sana outside of the Gene Therapy organization.

PRIMARY RESPONSIBILITIES
  • Work closely with the Sr. Scientist to plan and execute in vivo studies
  • Tissue collection and processing for downstream assays such as flow cytometry, histology and molecular work
  • Support in vitro work (e.g. cell culture) to enable in vivo studies
  • Data recording, analysis and reporting using proper software (e.g. Prism, FlowJo) and electronic notebook
  • Presentation of data to the team
  • Participate in creating a collaborative, rewarding work environment

QUALIFICATIONS

Required Qualifications
  • BS in biology or related discipline and 4+ years or 2+ years/MS of relevant research experience in an industry or academic setting
  • Experience with standard molecular biology and cell biology techniques: RNA isolation and reverse-transcription, qPCR, mammalian cell culture, staining for Flow Cytometry and Lentivirus transduction
  • Experience in working with mice: handling, injections (IV, IP, SC), bleeding, tissue harvest
  • Experience in developing in vitro and in vivo assays and deploying at scale in a collaborative research environment
  • Demonstrated experience with relevant software: Microsoft Word, Excel, PowerPoint, Graphpad Prism, FlowJo software
  • Strong interpersonal skills and adaptable communication style
  • Strong organizational, record keeping, and data documentation skills
  • Excellent oral and written communication skills, attention to detail and data quality, and experience working on diverse collaborative teams

Preferred Qualifications
  • BS or MS degree in immunology
  • Experience in T cell immunology and/or Hematopoietic Stem Cells
  • Experience with immune cell profiling using flow cytometry techniques