Associate Scientist II/Scientist I, Cancer Biology

South San Francisco, CA, United States
Oct 29, 2020
Required Education
Bachelors Degree
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .


AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 30,000 people worldwide and markets medicines in more than 170 countries.


Oncology is a key therapeutic area for AbbVie, with a portfolio consisting of three marketed products - Imbruvica, Venclexta, and Empliciti - and a pipeline containing multiple promising new molecules that are being studied in nearly 200 clinical trials in 19 different types of cancer.

AbbVie is expanding its oncology hub on the West Coast, with three sites in the San Francisco Bay Area (Redwood City, South San Francisco, and Sunnyvale) focused on the discovery and development of novel oncology therapies. More than 1,000 AbbVie scientists, statisticians, clinicians, and product developers with strong entrepreneurial roots work across these three sites. They combine their expertise in immuno-oncology, stem cells, and cell-signaling with their knowledge of bispecific antibodies, antibody-drug conjugates (ADCs), and covalent-inhibitor technologies to discover and develop novel cancer treatments.

AbbVie-South San Francisco is comprised of a multi-disciplinary team of world-class scientists and focused on developing novel targeted therapeutics in oncology, including antibody-drug conjugates. We are looking for an Associate Scientist II/Scientist I with experience in flow cytometry, PDX (Patient Derived Xenograft) models and cell culture, as well as standard molecular biology and biochemical techniques. Above all, we are looking for a highly motivated and collaborative individual with a passion for oncology research, who enjoys working in a fast-paced and highly dynamic working environment.

  • Manage and characterize PDX bank and cell line collection
  • Work with the in vivo team to support in vivo efficacy studies
  • Perform daily FACS-based analysis of PDX tumors
  • Help maintain functional flow cytometers
  • Perform cell-based or biochemical assays on a tight schedule
  • Design, execute and analyze research studies using PDX models
  • Report assay results to team and present regularly at group meetings


  • BS degree and 3-5 years or MS degree and 0-2 years of relevant experience
  • Technical expertise in cell and molecular biology and/or cancer biology
  • Experience with mouse models of cancer, including PDX (Patient Derived Xenograft) models
  • Excellent laboratory, record keeping, data analysis, and critical thinking skills
  • Ability to plan, execute, and troubleshoot experiments
  • Ability to manage more than one project at any given time and to work successfully in a cross-functional and highly collaborative team environment
  • Exceptional communication, both speech and writing, to a variety of audience types
  • Excellent working knowledge of Microsoft Word, Excel, PowerPoint, and GraphPad Prism

**Equal Opportunity Employer Minorities/Women/Veterans/Disabled**

Significant Work Activities
Awkward/forceful/repetitive motions (arms above shoulders, bent wrists, etc.)
Yes, 10 % of the Time
Job Type
Job Level Code
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.