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Scientist, Research Informatics

Employer
MyoKardia, Inc (acquired by BMS)
Location
Brisbane, California, United States
Start date
Oct 29, 2020

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Discipline
Regulatory, Science/R&D, Biotechnology
Required Education
Bachelors Degree
Position Type
Full time
Hotbed
Biotech Bay

Job Details

Myokardia is seeking an experienced Research Informatics expert to manage experiment-project data and applications for the Biology Teams. The successful candidate will apply their Lab Bench experience and work closely with research scientists to identify and prioritize needs. You will help fellow scientists effectively use Myokardia's tools and applications to capture, analyze query and report scientific data that enables actionable insights for current and future work. This position will help lead the strategy and execution around data lifecycle management, data standards, analytics infrastructure, ongoing data operations and informatics systems.

Major Responsibilities:
  • Partner closely with scientists and other informaticians to envision, implement, and support informatics tools and business process that enhance our ability to acquire, store, transform, visualize, and analyze data.
  • Research Informatics liaison to project teams, collaborators, partners and external CRO's.
  • Lead Research Informatics Scientific Applications Team
  • Help create new Assay Protocols in Dotmatics Studies and/or ELN based applications
  • Provides hands-on scientific application support
  • Support project teams in implementation of scientific and operational informatics solutions for multiple functions to ensure data accessibility, quality and integrity.
  • Implement data visualizations to extract the full value of our scientific and operational data.
  • Communicates issues, technical discrepancies, and projects status updates to team and scientific stakeholders.
  • Implement ‘quick and easy' informatics solutions that solve specific problems fast and efficiently

Requirements:

A BS/MS/PhD in Life Sciences and minimum of 5-8 plus years of Application and Database management expertise in the biopharmaceutical industry. The successful candidate will draw on their laboratory bench experience and demonstrable informatics skills and be able to:
  • Show thorough understanding of R&D processes and Drug Discovery data life cycle.
  • Lab Bench experience and familiarity with common biochemical, cell, gene based and in-vivo immuno-assays including data derived from such experiments.
  • Ability to help troubleshoot common data analysis workflows and comfortable working with common results and parameters like IC50s, equilibrium constant calculations, 4-paramater fit curves etc.
  • Proven track record of supporting scientific informatics efforts and ELN workflow.
  • Familiarity with current informatics applications and systems, relational and non-relational databases, scripting languages, and data visualization tools. Such as:
    • Dotmatics suite of apps (Browser, Studies, Vortex, Bioregister)
    • ChemAxon's compound management and Titian Mosaic Inventory
    • Oracle, MySQL, Postgres, SQLServer, Perl, Python, Java, VB, C/C++
  • Working knowledge of scientific research application development cycles and data management principles.
  • Excellent people and communication skills.

Company

MyoKardia’s mission is to change the world for people with serious cardiovascular disease through bold and innovative science. MyoKardia is a clinical-stage bio pharmaceutical company discovering and developing targeted therapies for the treatment of serious cardiovascular diseases. The company is pioneering a precision medicine approach to its discovery and development efforts by 1) understanding the bio mechanical underpinnings of disease; 2) targeting the proteins that modulate a given condition; 3) identifying patient populations with shared disease characteristics; and 4) applying learnings from research and clinical studies to inform and guide pipeline growth and product advancement. MyoKardia’s initial focus is on small molecule therapeutics aimed at the proteins of the heart that modulate cardiac muscle contraction to address diseases driven by excessive contraction, impaired relaxation, or insufficient contraction. Among its discoveries are three clinical-stage therapeutics: mavacamten (formerly MYK-461); danicamtiv (formerly MYK-491) and MYK-224. Founded in September 2012 MyoKardia is headquartered in Brisbane, CA.

 

MyoKardia Life

MyoKardia Life 2

MyoKardia Office 4MyoKardia Office 2MyoKardia Office 1

Company info
Website
Phone
650-741-0900
Location
1000 Sierra Point Parkway
Brisbane, CA 94005
US

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