Associate Scientist, Analytical Method Development and Characterization (Biologics)

Location
San Francisco, CA, United States
Posted
Oct 29, 2020
Ref
5257-396-R
Hotbed
Biotech Bay
Required Education
Doctorate/PHD/MD
Position Type
Full time
Position Overview

Nektar has an exciting opportunity for an Associate Scientist, Biologics Analytical Development to join their team.

Associate Scientist, Biologics Analytical Development, part of Nektar Biologics CMC organization is responsible for product characterization, analytical method development/qualification of proteins and protein-conjugates for Nektar Biologic products in pre-clinical and clinical development stages. Conducts and collaborates with others on analytical issues relevant to long-term objectives and concerns. Develops testing methodologies to support process development of drug substance and drug product.

This position contributes to and supports the company's research development and manufacturing to create high value therapeutics to address unmet medical needs.

The successful candidate will be responsible for:
  • Develop and qualify analytical methods to support drug development activities
  • Characterize protein and protein polymer conjugates using various analytical techniques
  • Assist process development scientists to characterize and monitor in-process purification
  • Transfer analytical methods to internal QC group or CRO for drug substance and drug product release testing
  • Summarize experimental data and write technical reports
Requires a PhD in a scientific discipline and 0-2 years related experience; MS in a scientific discipline and a minimum of 3+ years related experience; BS in a scientific discipline and minimum 6+ years related experience. Must have extensive hands-on experience in HPLC Analysis of Proteins. Must have knowledge and hands-on experience in analytical method development and characterization for biologics. Experience in HPLC separation methods such as ion exchange, reversed phase, and size exclusion chromatography, and capillary electrophoresis for proteins is highly desirable. Must be able to demonstrate potential for technical proficiency, scientific creativity, collaboration with others and independent thought. Must be able to clearly communicate scientific information both written and oral. Experience in technology transfer to internal QC lab or CRO in support of drug substance/drug product release testing is highly desirable Good computer skills are required. Working knowledge of MS word, Excel, Power point.

We are an Equal Opportunity Employer and do not discriminate against applicants due to race, ethnicity, gender, veteran status, or on the basis of disability or any other federal, state or local protected class. Nektar Therapeutics will consider for employment qualified applicants with criminal histories in the manner proscribed by the San Francisco Fair Chance Ordinance.