Research Specialist B
A position is available at the University of Pennsylvania for a motivated and detail-oriented team-player. The Melenhorst laboratory is a newly established research group in the Center for Cellular Immunotherapies (CCI) known as the Translational Immunology Laboratory (TIL). The research in TIL is aimed at a) studying the tumor microenvironment in chronic lymphocytic leukemia and other malignancies using single cell genomic and proteomic technologies and b) understanding and improving the anti-tumor efficacy of adoptively transferred gene-modified T cells through correlative, mechanistic, and pre-clinical studies, and partly through functional genomics approaches. The laboratory has identified mechanisms of response to CAR T cell therapy in chronic lymphocytic leukemia and developed an in vitro screening system to identify the most potent precursor cells of CAR T cells. We are hiring a highly motivated research specialist B with a strong background in human T cell culture and flow cytometry. This position will assist in maintaining laboratory reagent and supply inventories, keeping laboratory records (i.e., regulatory and administrative documents) up-to-date; processing fresh cells from leukemia and myeloma patients, perform cell cultures, prepare lentiviral constructs, flow cytometric experiments (data acquisition) and electronic and magnetic sorts. Additionally, this individual will assist with the in vivo experiments as carried out by the post-doc.
BA degree in science and 1-3 years of demonstrated experience in academic cellular immunology research or an equivalent combination of experience and education required. Master’s degree preferred. A broad knowledge base of immunology including the biology of human T cells is desired. Demonstrated abilities to multi-task and exhibiting effective time management skills are required. Prior laboratory experience including mammalian tissue culture is required. Specialized training on utilizing multi-color flow cytometric instruments and data analysis using Flow Jo software is preferred. Hands-on experience with quantitative PCR platforms preferred. Candidate must exhibit excellent computer skills, including expertise in Microsoft Office applications. Preference will be given to candidates who indicate a strong desire to build a career in the medical field. Background check required after a conditional job offer is made. Consideration of the background check will be tailored to the requirements of the job.
The University of Pennsylvania, the largest private employer in Philadelphia, is a world-renowned leader in education, research, and innovation. This historic, Ivy League school consistently ranks among the top 10 universities in the annual U.S. News & World Report survey. Penn has 12 highly-regarded schools that provide opportunities for undergraduate, graduate and continuing education, all influenced by Penn’s distinctive interdisciplinary approach to scholarship and learning.
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