AbbVie

Scientific Director, Human Genetics

Employer
AbbVie
Location
Lake County, IL, United States
Posted
Oct 26, 2020
Ref
1903252
Discipline
Science/R&D, Genetics
Required Education
Doctorate/PHD/MD
Position Type
Full time
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women's health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on Twitter , Facebook , Instagram , YouTube and LinkedIn .

The Genomics Research Center (GRC) is a newly created center of excellence for genetics and genomics that supports both Discovery and Development. The GRC plays an integral role towards our goal of developing world class genetics and genomics programs, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials. Two of the pillars of the GRC, the Department of Human Genetics and Pharmacogenomics are responsible for analyzing and interpreting data from large genetic sequencing databases to identify and characterize novel targets for the treatment of diseases across multiple therapeutic areas. We have an exciting opportunity for a scientific professional with medical expertise, based in North Chicago, IL reporting to the Head of Human Genetics and Clinical Genetics.

Key Responsibilities:
  • Provide expertise and coordinate clinical activities for human genetic databases. Represent the GRC on various clinical teams involved in defining and harmonizing clinical phenotype information captured in external databases.
  • Provide medical expertise for genetic, genomic or epigenetic studies applied to AbbVie clinical trials.
  • Collaborate with Medical Directors in Clinical Development to identify relevant questions and design studies related to drug response or disease etiology.
  • Collaborate with scientists across different Early Discovery therapeutic areas to interpret and incorporate genetic findings into new targets or for validation of existing targets
  • Provide support for external collaborations and consortia involving human cohorts

Qualifications

The level is commensurate with experience.

Basic:
  • MD or MD /PhD or other advanced degree required
  • Relevant experience in genomics, molecular biology, and Genomic Medicine (rare disease genetics and physiological genomics, systems biology of common complex disease)
  • Deep knowledge of translating genomic data into clinically relevant results.
  • Experience interpreting rare disease clinical data.
  • Experience with large-scale research projects involving next generation DNA sequencing data (e.g. whole exome and whole genome), array based genotype data in conjunction with results from informatics and wide array of molecular biology strategies.
  • Experience or strong knowledge of pharmacogenomics or pharmacogenetics.
  • Demonstrated effective written and verbal communication skills

Preferred:
  • A medical degree, with a strong background in genetic association studies, and family based genetic studies, knowledge of how drugs are developed.
  • The Candidate should have demonstrated ability to design and lead human genetics studies delivering novel genetic findings and medically relevant gene discoveries.
  • Experience working with large human genetic sequencing databases
  • Experience interpreting family-based and rare disease genetic studies
  • Strong oral and written communication skills in a collaborative environment
  • Minimal clinical trial or medical affairs experience in the pharmaceutical industry or academia or equivalent. 1-2 years of experience is preferred.

Key Leadership Competencies:
  • Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
  • Learns fast, grasps the "essence" and can change course quickly where indicated.
  • Raises the bar and is never satisfied with the status quo.
  • Creates a learning environment, open to suggestions and experimentation for improvement.
  • Embraces the ideas of others, nurtures innovation and manages innovation to reality

Significant Work Activities
Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day)
Travel
No
Job Type
Experienced
Schedule
Full-time
Job Level Code
D
Equal Employment Opportunity
At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.