Research Scientist, Vector Biology

Kite Pharma
Santa Monica, CA, United States
Oct 26, 2020
Required Education
Bachelors Degree
Position Type
Full time
Kite is continuing to hire for all open roles. Our interview process may be conducted virtually and some roles will be asked to temporarily work from home. Over the coming weeks and months, we will be implementing a phased approach to bringing employees back to site to ensure the health and safety of our teams.

For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job

Job Description

Kite Pharma Santa Monica is building a clinical vector production facility to enhance and broaden its gene therapy platform capabilities for the development of new cellular therapies targeting unmet oncology needs. Kite is seeking a Vector Biology Scientist to take on critical roles to support analytical design and characterization of retroviral and lentiviral vectors to enable vector process design and manufacturing. The person in this role will contribute to team projects, be a role model, mentor to junior staff, and take ownership of important analytical tasks.

Responsibilities and Duties
  • Establish strategy for vector analytics to follow USP/ICH/EU regulations, GMP/GLP requirements, and industry practices.
  • Provide technical leadership and expertise for vector method optimization, qualification and routine testing
  • Develop and mentor direct reports to provide analytical testing including but not limited to cell-based potency assays for the RVV- and LVV-based gene therapy product development and commercialization.
  • Interface with the process design and manufacturing teams in support of in-process testing and investigations.
  • Collaborate closely with the method development and quality control groups to support method development/optimization, characterization, troubleshooting, transfer and validation.
  • Author/review test methods, SOPs and technical protocols/reports.
  • Provide subject matter expertise into the method performance review.
  • Attend cross-functional team meetings as needed.
  • May contribute to the writing and review of regulatory submissions.

  • BS with 8+ years, or MS with 6+ years, or preferably PhD with 0+ years of industry experience in Cell Biology, Immunology, Molecular Biology, Virology or related fields.
  • Extensive hands-on experience with development and routine testing assays for vector release and characterization including data analysis.
  • Strong background in mammalian cell culture, flow cytometry, qPCR/ddPCR, and ELISA-based methods.
  • Experience with next-generation sequencing platforms, library construction and computational bioinformatics analyses (i.e. Illumina systems).
  • Familiar with data analysis software, such as MS Excel, PLA, JMP and SoftMax Pro.
  • Experience and ability to use DOE for assay optimization and robustness.
  • Knowledge of relevant USP/ICH/EU regulations, GMP/GLP requirements, and industry practices.
  • Highly collaborative team player who demonstrates open communication.
  • Strong scientific writing and presentation skills.
  • Experience with viral particle characterization/physical titer methods is preferred but not required.

Do you want to make a real difference in the world? Come help us in our quest to cure cancer! Everyone at Kite is grounded by this common goal. Every single day, we seek to establish a direct line between that purpose and our day-to-day work. Join us in our mission!


Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit Sign up to follow @KitePharma on Twitter at

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For Current Kite Pharma Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.